2YY8 | KnotProt

Genus: 54

Knot K +3₁

script 1 started

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JSmol exec jmolApplet1 start applet null

Jmol JavaScript applet jmolApplet1__1367312243984862__ initializing

Jmol getValue debug null

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AppletRegistry.checkIn(jmolApplet1__1367312243984862__)

vwrOptions:

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setting document base to "https://knotprot.cent.uw.edu.pl/view/2yy8/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

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appletId:jmolApplet1 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet1__1367312243984862__ ready

Help Knotting data interpretation Full screen

					Knot core range	Knot core length	Knot tails range	Slipknot tails range	Slipknot loops range	N-end length	C-end length	Type
view details				+3₁	80-124	45	1-79, 125-175			79	51	knot

Chain Sequence

MIVVLRLGHRPE-DKRVTTHVALTARAFGADGIIIASEEDEKVKESVEDVVKRWGGPFFIEFNRNWRKVMKEFTGVKVHLTMYGLHVDDVIEELKEKLKKGEDFMIIVGAEKVPREVYELADYNVAIGNQPHSEVAALAVLLDRLLEGKGLKKEFKGAKIKIVPQARGKKVVEVQ

Whole chain analysis

Help Knotoid data interpretation Full screen

Subchain analysis

Knotoid cutoff: 0.5

Knotoid matrix content: 1

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__1367312243984862__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__1367312243984862__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://knotprot.cent.uw.edu.pl/view/2yy8/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__1367312243984862__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"1367312243984862","bgcolor":"white" }

setting document base to "https://knotprot.cent.uw.edu.pl/view/2yy8/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__1367312243984862__ ready

script 1 started

platformSpeed = 8

Viewer cachePut cache://localLOAD_/static/knot_data/2yy8/A/2yy8_A.pdb.gz

Viewer cachePut https://knotprot.cent.uw.edu.pl/static/knot_data/2yy8/A/2yy8_A.pdb.gz

FileManager.getAtomSetCollectionFromFile(/static/knot_data/2yy8/A/2yy8_A.pdb.gz)

The Resolver thinks Pdb

loadScript /static/js/j2s/core/corebio.z.js

Time for openFile(/static/knot_data/2yy8/A/2yy8_A.pdb.gz): 397 ms

reading 174 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

174 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 26 ms

Adding embedded #jmolscript: select ({0:173});backbone only;select *;

platformSpeed = 7

cartoonsFancy = true

sheetSmoothing = 1.0

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loadScript /static/js/j2s/core/corescriptcmd.z.js

specularPower = 9

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antialiasDisplay = true

Script completed

Jmol script terminated

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loadScript /static/js/j2s/J/renderbio/BioMeshRenderer.js

loadScript /static/js/j2s/J/render/MeshRenderer.js

loadScript /static/js/j2s/J/shape/Mesh.js

Viewer cachePut cache://localLOAD_/static/knot_data/2yy8/A/2yy8_A.pdb.gz

Viewer cachePut https://knotprot.cent.uw.edu.pl/static/knot_data/2yy8/A/2yy8_A.pdb.gz

FileManager.getAtomSetCollectionFromFile(/static/knot_data/2yy8/A/2yy8_A.pdb.gz)

The Resolver thinks Pdb

Time for openFile(/static/knot_data/2yy8/A/2yy8_A.pdb.gz): 31 ms

reading 174 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

174 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 10 ms

Adding embedded #jmolscript: select ({0:173});backbone only;select *;

platformSpeed = 7

cartoonsFancy = true

sheetSmoothing = 1.0

traceAlpha = true

specularPower = 9

ambientPercent = 20

antialiasDisplay = true

Script completed

Jmol script terminated

Help Knotoid subchains data interpretation Full screen

					Knot core range	Knot core length	Knot tails range	Slipknot tails range	Slipknot loops range	N-end length	C-end length	Type
view details				3.1	77-124	48	1-76, 125-174			76	50	knot
view details				3.1	78-129	52		1-76, 147-174	77-77, 130-146	76	28	slipknot

sequence length	175
structure length	174
publication title	Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2'-O-methylcytidine at position 56 of tRNA pubmed doi rcsb
molecule tags	Transferase
molecule keywords	UPF0106 protein PH0461
source organism	Pyrococcus horikoshii
missing residues	13
total genus	Genus: 54
ec nomenclature	ec 2.1.1.206: tRNA (cytidine(56)-2'-O)-methyltransferase.
pdb deposition date	2007-04-27
KnotProt deposition date	2014-07-31

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01994	Trm56	tRNA ribose 2'-O-methyltransferase, aTrm56

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.1280.10	Alpha Beta	3-Layer(aba) Sandwich	Alpha/beta knot	Alpha/beta knot	2yy8A00

3IC6A 3QUVA 1NS5A 1V6ZA 1K3RA 3IEFA 3AI9X 1VHKA 3N4KA 4CNFB 1UALA 1V2XA 1GZ0A 1VH0A 1VHYA 1O6DA 1NXZA 2HA8A 3ILKA 1X7OA 3KY7A 1UAKA 3DCMX 3AXZA 2Z0YA 4IG6A 3KNUA 3GYQA 1MXIA 3E5YA 3NK7A 1UAMA 2QMMA 3AIAA 4CNEB 1TO0A 2I6DA 2YY8A 1ZJRA 1P9PA 1UAJA 4H3ZA 3L8UA 4CNGB 1J85A 4H3YA 2QWVA 3ONPA 3NK6A 3N4JA 1X7PA 4E8BA 4FAKA 3KTYA 2O3AA 2CX8A
chains in the KnotProt database with same CATH superfamily

#chains in the KnotProt database with same CATH superfamily
 3IC6 A;  3QUV A;  1NS5 A;  1V6Z A;  1K3R A;  3IEF A;  3AI9 X;  1VHK A;  3N4K A;  4CNF B;  1UAL A;  1V2X A;  1GZ0 A;  1VH0 A;  1VHY A;  1O6D A;  1NXZ A;  2HA8 A;  3ILK A;  1X7O A;  3KY7 A;  1UAK A;  3DCM X;  3AXZ A;  2Z0Y A;  4IG6 A;  3KNU A;  3GYQ A;  1MXI A;  3E5Y A;  3NK7 A;  1UAM A;  2QMM A;  3AIA A;  4CNE B;  1TO0 A;  2I6D A;  2YY8 A;  1ZJR A;  1P9P A;  1UAJ A;  4H3Z A;  3L8U A;  4CNG B;  1J85 A;  4H3Y A;  2QWV A;  3ONP A;  3NK6 A;  3N4J A;  1X7P A;  4E8B A;  4FAK A;  3KTY A;  2O3A A;  2CX8 A; 
#chains in the KnotProt database with same CATH topology
 3IC6 A;  3QUV A;  1NS5 A;  1V6Z A;  1K3R A;  3IEF A;  3AI9 X;  1VHK A;  3N4K A;  4CNF B;  1UAL A;  1V2X A;  1GZ0 A;  1VH0 A;  1VHY A;  1O6D A;  1NXZ A;  2HA8 A;  3ILK A;  1X7O A;  3KY7 A;  1UAK A;  3DCM X;  3AXZ A;  2Z0Y A;  4IG6 A;  3KNU A;  3GYQ A;  1MXI A;  3E5Y A;  3NK7 A;  1UAM A;  2QMM A;  3AIA A;  4CNE B;  1TO0 A;  2I6D A;  2YY8 A;  1ZJR A;  1P9P A;  1UAJ A;  4H3Z A;  3L8U A;  4CNG B;  1J85 A;  4H3Y A;  2QWV A;  3ONP A;  3NK6 A;  3N4J A;  1X7P A;  4E8B A;  4FAK A;  3KTY A;  2O3A A;  2CX8 A; 
#chains in the KnotProt database with same CATH homology
 3IC6 A;  3QUV A;  1NS5 A;  1V6Z A;  1K3R A;  3IEF A;  3AI9 X;  1VHK A;  3N4K A;  4CNF B;  1UAL A;  1V2X A;  1GZ0 A;  1VH0 A;  1VHY A;  1O6D A;  1NXZ A;  2HA8 A;  3ILK A;  1X7O A;  3KY7 A;  1UAK A;  3DCM X;  3AXZ A;  2Z0Y A;  4IG6 A;  3KNU A;  3GYQ A;  1MXI A;  3E5Y A;  3NK7 A;  1UAM A;  2QMM A;  3AIA A;  4CNE B;  1TO0 A;  2I6D A;  2YY8 A;  1ZJR A;  1P9P A;  1UAJ A;  4H3Z A;  3L8U A;  4CNG B;  1J85 A;  4H3Y A;  2QWV A;  3ONP A;  3NK6 A;  3N4J A;  1X7P A;  4E8B A;  4FAK A;  3KTY A;  2O3A A;  2CX8 A;

2O3AA
similar chains in the KnotProt database (40% sequence similarity)

8X6KA 9U46A
similar chains in the pdb database (40% sequence similarity)

#similar chains in the KnotProt database (40% sequence similarity)
2O3A A; 
#similar chains, but unknotted

#similar chains in the pdb database (40% sequence similarity)
8X6K A; 9U46 A;

2YY8A

Knot K +31

Chain Sequence

pfam database annotations

Knot K +3₁