3NK7A

Structure of the nosiheptide-resistance methyltransferase s-adenosyl-l-methionine complex
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 194-235 42 1-193, 236-274 193 39 knot
Chain Sequence
MTEPAIITNASDPAVQRIIDVTKHS---IKTTLIEDTEPLMECIRAGVQFIEVYGSSGTPLDPALLDLCRQREIPVRLIDVSIVNQLAKV------FGIARVPRPARLADIAERGGDVVVLDGVKIVGNIGAIVRTSLALGAAGIVLVDSDLATIADRRLLRASRGYVFSLPVVLADREEAVSFLRDNDIALMVLDTDGDLGVKDLGDRADRMALVFGSEKGGPSGLFQEASAGTVSIPMLSSTESLNVSVSVGIALHERSARNFAVRRAAAQA
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 186-228 43 1-185, 229-265 185 37 knot
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2.1 183-224 42 1-182 230-265 225-229 182 36 slipknot
view details
2.1 187-256 70 1-185, 263-265 186-186, 257-262 185 3 slipknot
missing residues 26-28, 88-93
publication title Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus
pubmed doi rcsb
structure length 265
molecule tags Transferase
source organism Streptomyces actuosus
sequence length 274
total genus Genus: 81
molecule keywords 23S rRNA methyltransferase
ec nomenclature ec 2.1.1.-:
pdb deposition date 2010-06-18
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1330.30 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; 60s Ribosomal Protein L30; Chain: A; 3nk7A01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3nk7A02
3KTYA 1K3RA 3E5YA 1VHKA 1UALA 1GZ0A 3IEFA 3AI9X 3KNUA 1UAJA 1ZJRA 3NK6A 2QMMA 2HA8A 3KY7A 1X7OA 1J85A 1NS5A 3IC6A 3NK7A 3ONPA 3AXZA 3GYQA 1NXZA 2Z0YA 3L8UA 4E8BA 3ILKA 3DCMX 3N4KA 4IG6A 1VHYA 2CX8A 3N4JA 3AIAA 1MXIA 4H3ZA 2I6DA 1X7PA 2O3AA 1P9PA 2YY8A 3QUVA 1V6ZA 4FAKA 1TO0A 1O6DA 2QWVA 1V2XA 1UAMA 4H3YA 1VH0A 1IPAA 1UAKA
chains in the KnotProt database with same CATH superfamily
3KTYA 1K3RA 3E5YA 1VHKA 1UALA 1GZ0A 3IEFA 3AI9X 3KNUA 1UAJA 1ZJRA 3NK6A 2QMMA 2HA8A 3KY7A 1X7OA 1J85A 1NS5A 3IC6A 3NK7A 3ONPA 3AXZA 3GYQA 1NXZA 2Z0YA 3L8UA 4E8BA 3ILKA 3DCMX 3N4KA 4IG6A 1VHYA 2CX8A 3N4JA 3AIAA 1MXIA 4H3ZA 2I6DA 1X7PA 2O3AA 1P9PA 2YY8A 3QUVA 1V6ZA 4FAKA 1TO0A 1O6DA 2QWVA 1V2XA 1UAMA 4H3YA 1VH0A 1IPAA 1UAKA
chains in the KnotProt database with same CATH topology
3KTYA 1K3RA 3E5YA 1VHKA 1UALA 1GZ0A 3IEFA 3AI9X 3KNUA 1UAJA 1ZJRA 3NK6A 2QMMA 2HA8A 3KY7A 1X7OA 1J85A 1NS5A 3IC6A 3NK7A 3ONPA 3AXZA 3GYQA 1NXZA 2Z0YA 3L8UA 4E8BA 3ILKA 3DCMX 3N4KA 4IG6A 1VHYA 2CX8A 3N4JA 3AIAA 1MXIA 4H3ZA 2I6DA 1X7PA 2O3AA 1P9PA 2YY8A 3QUVA 1V6ZA 4FAKA 1TO0A 1O6DA 2QWVA 1V2XA 1UAMA 4H3YA 1VH0A 1IPAA 1UAKA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 3KTY A;  1K3R A;  3E5Y A;  1VHK A;  1UAL A;  1GZ0 A;  3IEF A;  3AI9 X;  3KNU A;  1UAJ A;  1ZJR A;  3NK6 A;  2QMM A;  2HA8 A;  3KY7 A;  1X7O A;  1J85 A;  1NS5 A;  3IC6 A;  3NK7 A;  3ONP A;  3AXZ A;  3GYQ A;  1NXZ A;  2Z0Y A;  3L8U A;  4E8B A;  3ILK A;  3DCM X;  3N4K A;  4IG6 A;  1VHY A;  2CX8 A;  3N4J A;  3AIA A;  1MXI A;  4H3Z A;  2I6D A;  1X7P A;  2O3A A;  1P9P A;  2YY8 A;  3QUV A;  1V6Z A;  4FAK A;  1TO0 A;  1O6D A;  2QWV A;  1V2X A;  1UAM A;  4H3Y A;  1VH0 A;  1IPA A;  1UAK A; 
#chains in the KnotProt database with same CATH topology
 3KTY A;  1K3R A;  3E5Y A;  1VHK A;  1UAL A;  1GZ0 A;  3IEF A;  3AI9 X;  3KNU A;  1UAJ A;  1ZJR A;  3NK6 A;  2QMM A;  2HA8 A;  3KY7 A;  1X7O A;  1J85 A;  1NS5 A;  3IC6 A;  3NK7 A;  3ONP A;  3AXZ A;  3GYQ A;  1NXZ A;  2Z0Y A;  3L8U A;  4E8B A;  3ILK A;  3DCM X;  3N4K A;  4IG6 A;  1VHY A;  2CX8 A;  3N4J A;  3AIA A;  1MXI A;  4H3Z A;  2I6D A;  1X7P A;  2O3A A;  1P9P A;  2YY8 A;  3QUV A;  1V6Z A;  4FAK A;  1TO0 A;  1O6D A;  2QWV A;  1V2X A;  1UAM A;  4H3Y A;  1VH0 A;  1IPA A;  1UAK A; 
#chains in the KnotProt database with same CATH homology
 3KTY A;  1K3R A;  3E5Y A;  1VHK A;  1UAL A;  1GZ0 A;  3IEF A;  3AI9 X;  3KNU A;  1UAJ A;  1ZJR A;  3NK6 A;  2QMM A;  2HA8 A;  3KY7 A;  1X7O A;  1J85 A;  1NS5 A;  3IC6 A;  3NK7 A;  3ONP A;  3AXZ A;  3GYQ A;  1NXZ A;  2Z0Y A;  3L8U A;  4E8B A;  3ILK A;  3DCM X;  3N4K A;  4IG6 A;  1VHY A;  2CX8 A;  3N4J A;  3AIA A;  1MXI A;  4H3Z A;  2I6D A;  1X7P A;  2O3A A;  1P9P A;  2YY8 A;  3QUV A;  1V6Z A;  4FAK A;  1TO0 A;  1O6D A;  2QWV A;  1V2X A;  1UAM A;  4H3Y A;  1VH0 A;  1IPA A;  1UAK A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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