4H3ZA

Crystal structure of a symmetric dimer of a trna (guanine-(n(1)-)-methyltransferase from burkholderia phymatum bound to s-adenosyl homocystein in both half-sites
Genus: 81
Knot K +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 92-135 44 1-91, 136-255 91 120 knot
Chain Sequence
SMQFDIVTLFPDMFRALTDWGITSRAAKQERYGLRTWNPRDFTTDNYRTIDDRPYGGGPGMVMLARPLEDAINAAKAAQAEQGIGGARVVMMSPQGATLNHDKVMRFAAEPGLILLCGRYEAIDQRLIDRVVDEEVSLGDFVLSGGELPAMALIDAVVRHLPGVLN------QDSFVDGLLDCPHYTRPEEYDGVRVPDVLLGGHHAEIEQWRRREALRNTWLKRPDLIVQARKNKLLSRADEAWLASLAKDASK
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 91-136 46 1-90, 137-249 90 113 knot
sequence length 255
structure length 249
publication title Combining functional and structural genomics to sample the essential Burkholderia structome.
pubmed doi rcsb
molecule tags Transferase
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
source organism Burkholderia phymatum
missing residues 167-172
total genus Genus: 81
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2012-09-14
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4h3zA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4h3zA01
1UAMA 3AIAA 3NK7A 3KNUA 1J85A 2HA8A 1UAJA 4IG6A 3DCMX 1TO0A 1O6DA 2I6DA 1NXZA 3L8UA 1X7OA 1VH0A 1GZ0A 1MXIA 1V6ZA 4H3YA 4FAKA 3E5YA 4CNGB 1K3RA 2O3AA 3ILKA 1ZJRA 2CX8A 3N4KA 1P9PA 1VHYA 4H3ZA 3IEFA 1VHKA 1X7PA 2QMMA 3N4JA 2QWVA 2YY8A 4CNFB 4CNEB 2Z0YA 1NS5A 3KTYA 3KY7A 3AXZA 3GYQA 3AI9X 3NK6A 4E8BA 1UALA 1UAKA 1V2XA 3ONPA 3IC6A 3QUVA
chains in the KnotProt database with same CATH superfamily
1UAMA 3AIAA 3NK7A 3KNUA 1J85A 2HA8A 1UAJA 4IG6A 3DCMX 1TO0A 1O6DA 2I6DA 1NXZA 3L8UA 1X7OA 1VH0A 1GZ0A 1MXIA 1V6ZA 4H3YA 4FAKA 3E5YA 4CNGB 1K3RA 2O3AA 3ILKA 1ZJRA 2CX8A 3N4KA 1P9PA 1VHYA 4H3ZA 3IEFA 1VHKA 1X7PA 2QMMA 3N4JA 2QWVA 2YY8A 4CNFB 4CNEB 2Z0YA 1NS5A 3KTYA 3KY7A 3AXZA 3GYQA 3AI9X 3NK6A 4E8BA 1UALA 1UAKA 1V2XA 3ONPA 3IC6A 3QUVA
chains in the KnotProt database with same CATH topology
1UAMA 3AIAA 3NK7A 3KNUA 1J85A 2HA8A 1UAJA 4IG6A 3DCMX 1TO0A 1O6DA 2I6DA 1NXZA 3L8UA 1X7OA 1VH0A 1GZ0A 1MXIA 1V6ZA 4H3YA 4FAKA 3E5YA 4CNGB 1K3RA 2O3AA 3ILKA 1ZJRA 2CX8A 3N4KA 1P9PA 1VHYA 4H3ZA 3IEFA 1VHKA 1X7PA 2QMMA 3N4JA 2QWVA 2YY8A 4CNFB 4CNEB 2Z0YA 1NS5A 3KTYA 3KY7A 3AXZA 3GYQA 3AI9X 3NK6A 4E8BA 1UALA 1UAKA 1V2XA 3ONPA 3IC6A 3QUVA
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 1UAM A;  3AIA A;  3NK7 A;  3KNU A;  1J85 A;  2HA8 A;  1UAJ A;  4IG6 A;  3DCM X;  1TO0 A;  1O6D A;  2I6D A;  1NXZ A;  3L8U A;  1X7O A;  1VH0 A;  1GZ0 A;  1MXI A;  1V6Z A;  4H3Y A;  4FAK A;  3E5Y A;  4CNG B;  1K3R A;  2O3A A;  3ILK A;  1ZJR A;  2CX8 A;  3N4K A;  1P9P A;  1VHY A;  4H3Z A;  3IEF A;  1VHK A;  1X7P A;  2QMM A;  3N4J A;  2QWV A;  2YY8 A;  4CNF B;  4CNE B;  2Z0Y A;  1NS5 A;  3KTY A;  3KY7 A;  3AXZ A;  3GYQ A;  3AI9 X;  3NK6 A;  4E8B A;  1UAL A;  1UAK A;  1V2X A;  3ONP A;  3IC6 A;  3QUV A; 
#chains in the KnotProt database with same CATH topology
 1UAM A;  3AIA A;  3NK7 A;  3KNU A;  1J85 A;  2HA8 A;  1UAJ A;  4IG6 A;  3DCM X;  1TO0 A;  1O6D A;  2I6D A;  1NXZ A;  3L8U A;  1X7O A;  1VH0 A;  1GZ0 A;  1MXI A;  1V6Z A;  4H3Y A;  4FAK A;  3E5Y A;  4CNG B;  1K3R A;  2O3A A;  3ILK A;  1ZJR A;  2CX8 A;  3N4K A;  1P9P A;  1VHY A;  4H3Z A;  3IEF A;  1VHK A;  1X7P A;  2QMM A;  3N4J A;  2QWV A;  2YY8 A;  4CNF B;  4CNE B;  2Z0Y A;  1NS5 A;  3KTY A;  3KY7 A;  3AXZ A;  3GYQ A;  3AI9 X;  3NK6 A;  4E8B A;  1UAL A;  1UAK A;  1V2X A;  3ONP A;  3IC6 A;  3QUV A; 
#chains in the KnotProt database with same CATH homology
 1UAM A;  3AIA A;  3NK7 A;  3KNU A;  1J85 A;  2HA8 A;  1UAJ A;  4IG6 A;  3DCM X;  1TO0 A;  1O6D A;  2I6D A;  1NXZ A;  3L8U A;  1X7O A;  1VH0 A;  1GZ0 A;  1MXI A;  1V6Z A;  4H3Y A;  4FAK A;  3E5Y A;  4CNG B;  1K3R A;  2O3A A;  3ILK A;  1ZJR A;  2CX8 A;  3N4K A;  1P9P A;  1VHY A;  4H3Z A;  3IEF A;  1VHK A;  1X7P A;  2QMM A;  3N4J A;  2QWV A;  2YY8 A;  4CNF B;  4CNE B;  2Z0Y A;  1NS5 A;  3KTY A;  3KY7 A;  3AXZ A;  3GYQ A;  3AI9 X;  3NK6 A;  4E8B A;  1UAL A;  1UAK A;  1V2X A;  3ONP A;  3IC6 A;  3QUV A;
1UAJA 1UAKA 1UALA 1UAMA 3AXZA 4H3ZA 4YQDA 4YVGA 4YVHA
similar chains in the KnotProt database (40% sequence similarity)
None
similar chains in the pdb database (40% sequence similarity)

  
#similar chains in the KnotProt database (40% sequence similarity)
1UAJ A; 1UAK A; 1UAL A; 1UAM A; 3AXZ A; 4H3Z A; 4YQD A; 4YVG A; 4YVH A; 
#similar chains, but unknotted

#similar chains in the pdb database (40% sequence similarity)
How to cite
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