4IG6A

Crystal structure of a trna (guanine-n1)-methyltransferase from anaplasma phagocytophilum bound to s-adenosylhomocysteine
Genus: 66
Knot K +31

  Help Knotting data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 86-130 45 1-85, 131-223 85 93 knot
Chain Sequence
SMIFNVLTIFPQMFPGPLGVSNLGSALKKGLWTLNVFDIRAFANNKHNTVDDTPYGGGPGMLLRADVLGRCIDEVLSLHPNTKLMFTSPRGVSFTQDIARQTMNFDNITLLCGRFEGIDERVVDFYKLQEVSIGDYVLSGGELAAMVIIDTCVRMVPGVIGNAESLKQESMEGSLEYPQYTRPASWKGMEVPEVLLTGNHGEIEKWRRNASLSITAARRPDLL
Whole chain analysis

  Help Knotoid data interpretation Full screen
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


  Help Knotoid subchains data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 86-132 47 1-85, 133-223 85 91 knot
view details
2.1 84-128 45 1-83 134-223 129-133 83 90 slipknot
view details
2.1 88-157 70 1-85, 166-223 86-87, 158-165 85 58 slipknot
view details
2.1 88-169 82 1-85, 181-223 86-87, 170-180 85 43 slipknot
sequence length 223
structure length 223
publication title Crystal structure of a tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum bound to S-adenosylhomocysteine
rcsb
molecule tags Transferase/transferase inhibitor
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
source organism Anaplasma phagocytophilum
total genus Genus: 66
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2012-12-16
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ig6A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ig6A01
4CNEB 3AIAA 3N4JA 1V2XA 1TO0A 3ONPA 1UAJA 1VHYA 3N4KA 1V6ZA 3GYQA 4CNGB 2O3AA 3IEFA 1UAKA 1MXIA 3ILKA 3L8UA 2I6DA 1O6DA 1NXZA 1X7OA 3DCMX 2QMMA 2CX8A 4H3YA 3KY7A 4IG6A 1UALA 1VHKA 3NK7A 2Z0YA 1J85A 2YY8A 1K3RA 1VH0A 4FAKA 1UAMA 3QUVA 1NS5A 1X7PA 3AI9X 3NK6A 4CNFB 4E8BA 3IC6A 1ZJRA 3E5YA 1GZ0A 3KTYA 3KNUA 3AXZA 2QWVA 1P9PA 4H3ZA 2HA8A
chains in the KnotProt database with same CATH superfamily
4CNEB 3AIAA 3N4JA 1V2XA 1TO0A 3ONPA 1UAJA 1VHYA 3N4KA 1V6ZA 3GYQA 4CNGB 2O3AA 3IEFA 1UAKA 1MXIA 3ILKA 3L8UA 2I6DA 1O6DA 1NXZA 1X7OA 3DCMX 2QMMA 2CX8A 4H3YA 3KY7A 4IG6A 1UALA 1VHKA 3NK7A 2Z0YA 1J85A 2YY8A 1K3RA 1VH0A 4FAKA 1UAMA 3QUVA 1NS5A 1X7PA 3AI9X 3NK6A 4CNFB 4E8BA 3IC6A 1ZJRA 3E5YA 1GZ0A 3KTYA 3KNUA 3AXZA 2QWVA 1P9PA 4H3ZA 2HA8A
chains in the KnotProt database with same CATH topology
4CNEB 3AIAA 3N4JA 1V2XA 1TO0A 3ONPA 1UAJA 1VHYA 3N4KA 1V6ZA 3GYQA 4CNGB 2O3AA 3IEFA 1UAKA 1MXIA 3ILKA 3L8UA 2I6DA 1O6DA 1NXZA 1X7OA 3DCMX 2QMMA 2CX8A 4H3YA 3KY7A 4IG6A 1UALA 1VHKA 3NK7A 2Z0YA 1J85A 2YY8A 1K3RA 1VH0A 4FAKA 1UAMA 3QUVA 1NS5A 1X7PA 3AI9X 3NK6A 4CNFB 4E8BA 3IC6A 1ZJRA 3E5YA 1GZ0A 3KTYA 3KNUA 3AXZA 2QWVA 1P9PA 4H3ZA 2HA8A
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 4CNE B;  3AIA A;  3N4J A;  1V2X A;  1TO0 A;  3ONP A;  1UAJ A;  1VHY A;  3N4K A;  1V6Z A;  3GYQ A;  4CNG B;  2O3A A;  3IEF A;  1UAK A;  1MXI A;  3ILK A;  3L8U A;  2I6D A;  1O6D A;  1NXZ A;  1X7O A;  3DCM X;  2QMM A;  2CX8 A;  4H3Y A;  3KY7 A;  4IG6 A;  1UAL A;  1VHK A;  3NK7 A;  2Z0Y A;  1J85 A;  2YY8 A;  1K3R A;  1VH0 A;  4FAK A;  1UAM A;  3QUV A;  1NS5 A;  1X7P A;  3AI9 X;  3NK6 A;  4CNF B;  4E8B A;  3IC6 A;  1ZJR A;  3E5Y A;  1GZ0 A;  3KTY A;  3KNU A;  3AXZ A;  2QWV A;  1P9P A;  4H3Z A;  2HA8 A; 
#chains in the KnotProt database with same CATH topology
 4CNE B;  3AIA A;  3N4J A;  1V2X A;  1TO0 A;  3ONP A;  1UAJ A;  1VHY A;  3N4K A;  1V6Z A;  3GYQ A;  4CNG B;  2O3A A;  3IEF A;  1UAK A;  1MXI A;  3ILK A;  3L8U A;  2I6D A;  1O6D A;  1NXZ A;  1X7O A;  3DCM X;  2QMM A;  2CX8 A;  4H3Y A;  3KY7 A;  4IG6 A;  1UAL A;  1VHK A;  3NK7 A;  2Z0Y A;  1J85 A;  2YY8 A;  1K3R A;  1VH0 A;  4FAK A;  1UAM A;  3QUV A;  1NS5 A;  1X7P A;  3AI9 X;  3NK6 A;  4CNF B;  4E8B A;  3IC6 A;  1ZJR A;  3E5Y A;  1GZ0 A;  3KTY A;  3KNU A;  3AXZ A;  2QWV A;  1P9P A;  4H3Z A;  2HA8 A; 
#chains in the KnotProt database with same CATH homology
 4CNE B;  3AIA A;  3N4J A;  1V2X A;  1TO0 A;  3ONP A;  1UAJ A;  1VHY A;  3N4K A;  1V6Z A;  3GYQ A;  4CNG B;  2O3A A;  3IEF A;  1UAK A;  1MXI A;  3ILK A;  3L8U A;  2I6D A;  1O6D A;  1NXZ A;  1X7O A;  3DCM X;  2QMM A;  2CX8 A;  4H3Y A;  3KY7 A;  4IG6 A;  1UAL A;  1VHK A;  3NK7 A;  2Z0Y A;  1J85 A;  2YY8 A;  1K3R A;  1VH0 A;  4FAK A;  1UAM A;  3QUV A;  1NS5 A;  1X7P A;  3AI9 X;  3NK6 A;  4CNF B;  4E8B A;  3IC6 A;  1ZJR A;  3E5Y A;  1GZ0 A;  3KTY A;  3KNU A;  3AXZ A;  2QWV A;  1P9P A;  4H3Z A;  2HA8 A;
...loading similar chains, please wait...
similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling