1EW9A

Alkaline phosphatase (e.c. 3.1.3.1) complex with mercaptomethyl phosphonate
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 46-369 324 1-45 420-449 370-419 45 30 slipknot
Chain Sequence
TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 48-373 326 1-47 412-449 374-411 47 38 slipknot
view details
3.1 44-412 369 1-43 420-449 413-419 43 30 slipknot
view details
2.1 13-368 356 1-4, 374-449 5-12, 369-373 4 76 slipknot
view details
2.1 31-367 337 1-16, 373-449 17-30, 368-372 16 77 slipknot
view details
2.1 42-367 326 1-31, 374-449 32-41, 368-373 31 76 slipknot
sequence length 449
structure length 449
publication title Alternate modes of binding in two crystal structures of alkaline phosphatase-inhibitor complexes.
pubmed rcsb
molecule tags Hydrolase
molecule keywords ALKALINE PHOSPHATASE
source organism Escherichia coli
total genus Genus: 159
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2000-04-24
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1ew9A00
3BDHA 3M8ZA 1ALIA 3M8WA 1ANIA 1AJBA 4FDJA 3DPCA 1ALKA 1EW2A 1ZEDA 1HQAA 1EW9A 1E33P 3UNYA 1HDHA 3T02A 1Y7AA 3T00A 1ZEFA 1ED9A 1SHNA 1EW8A 3TX0A 3UN3A 1ELZA 2GLQA 1KH5A 1KHLA 3UO0A 1Y6VA 3UN5A 3OT9A 3UN2A 1ZEBA 1N2KA 2G9YA 3MK1A 3TWZA 3BDFA 1E1ZP 3T01A 3ED4A 1B8JA 2QZUA 1KH9A 1KHJA 1ALJA 3M8YA 1KH4A 3CMRA 1E3CP 1O99A 3IGYB 1AUKA 3IGZB 1N2LA 2GA3A 2IFYA 3SZZA 1KHKA 3M7VA 1ELYA 3MK2A 1P49A 1KHNA 3BDGA 4FDIA 1KH7A 3NVLA 1E2SP 1URAA 1EJJA 1K7HA 3DYCA 1ELXA 1AJCA 1AJAA 2ANHA 3MK0A 1EQJA 1SHQA 1ED8A 1ANJA 1AJDA 1O98A 3BDGB 3SZYA 1HJKA 1EI6A 1FSUA 1URBA
chains in the KnotProt database with same CATH superfamily
3BDHA 3M8ZA 1ALIA 3M8WA 1ANIA 1AJBA 4FDJA 3DPCA 1ALKA 1EW2A 1ZEDA 1HQAA 1EW9A 1E33P 3UNYA 1HDHA 3T02A 1Y7AA 3T00A 1ZEFA 1ED9A 1SHNA 1EW8A 3TX0A 3UN3A 1ELZA 2GLQA 1KH5A 1KHLA 3UO0A 1Y6VA 3UN5A 3OT9A 3UN2A 1ZEBA 1N2KA 2G9YA 3MK1A 3TWZA 3BDFA 1E1ZP 3T01A 3ED4A 1B8JA 2QZUA 1KH9A 1KHJA 1ALJA 3M8YA 1KH4A 3CMRA 1E3CP 1O99A 3IGYB 1AUKA 3IGZB 1N2LA 2GA3A 2IFYA 3SZZA 1KHKA 3M7VA 1ELYA 3MK2A 1P49A 1KHNA 3BDGA 4FDIA 1KH7A 3NVLA 1E2SP 1URAA 1EJJA 1K7HA 3DYCA 1ELXA 1AJCA 1AJAA 2ANHA 3MK0A 1EQJA 1SHQA 1ED8A 1ANJA 1AJDA 1O98A 3BDGB 3SZYA 1HJKA 1EI6A 1FSUA 1URBA
chains in the KnotProt database with same CATH topology
3BDHA 3M8ZA 1ALIA 3M8WA 1ANIA 1AJBA 4FDJA 3DPCA 1ALKA 1EW2A 1ZEDA 1HQAA 1EW9A 1E33P 3UNYA 1HDHA 3T02A 1Y7AA 3T00A 1ZEFA 1ED9A 1SHNA 1EW8A 3TX0A 3UN3A 1ELZA 2GLQA 1KH5A 1KHLA 3UO0A 1Y6VA 3UN5A 3OT9A 3UN2A 1ZEBA 1N2KA 2G9YA 3MK1A 3TWZA 3BDFA 1E1ZP 3T01A 3ED4A 1B8JA 2QZUA 1KH9A 1KHJA 1ALJA 3M8YA 1KH4A 3CMRA 1E3CP 1O99A 3IGYB 1AUKA 3IGZB 1N2LA 2GA3A 2IFYA 3SZZA 1KHKA 3M7VA 1ELYA 3MK2A 1P49A 1KHNA 3BDGA 4FDIA 1KH7A 3NVLA 1E2SP 1URAA 1EJJA 1K7HA 3DYCA 1ELXA 1AJCA 1AJAA 2ANHA 3MK0A 1EQJA 1SHQA 1ED8A 1ANJA 1AJDA 1O98A 3BDGB 3SZYA 1HJKA 1EI6A 1FSUA 1URBA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 3BDH A;  3M8Z A;  1ALI A;  3M8W A;  1ANI A;  1AJB A;  4FDJ A;  3DPC A;  1ALK A;  1EW2 A;  1ZED A;  1HQA A;  1EW9 A;  1E33 P;  3UNY A;  1HDH A;  3T02 A;  1Y7A A;  3T00 A;  1ZEF A;  1ED9 A;  1SHN A;  1EW8 A;  3TX0 A;  3UN3 A;  1ELZ A;  2GLQ A;  1KH5 A;  1KHL A;  3UO0 A;  1Y6V A;  3UN5 A;  3OT9 A;  3UN2 A;  1ZEB A;  1N2K A;  2G9Y A;  3MK1 A;  3TWZ A;  3BDF A;  1E1Z P;  3T01 A;  3ED4 A;  1B8J A;  2QZU A;  1KH9 A;  1KHJ A;  1ALJ A;  3M8Y A;  1KH4 A;  3CMR A;  1E3C P;  1O99 A;  3IGY B;  1AUK A;  3IGZ B;  1N2L A;  2GA3 A;  2IFY A;  3SZZ A;  1KHK A;  3M7V A;  1ELY A;  3MK2 A;  1P49 A;  1KHN A;  3BDG A;  4FDI A;  1KH7 A;  3NVL A;  1E2S P;  1URA A;  1EJJ A;  1K7H A;  3DYC A;  1ELX A;  1AJC A;  1AJA A;  2ANH A;  3MK0 A;  1EQJ A;  1SHQ A;  1ED8 A;  1ANJ A;  1AJD A;  1O98 A;  3BDG B;  3SZY A;  1HJK A;  1EI6 A;  1FSU A;  1URB A; 
#chains in the KnotProt database with same CATH topology
 3BDH A;  3M8Z A;  1ALI A;  3M8W A;  1ANI A;  1AJB A;  4FDJ A;  3DPC A;  1ALK A;  1EW2 A;  1ZED A;  1HQA A;  1EW9 A;  1E33 P;  3UNY A;  1HDH A;  3T02 A;  1Y7A A;  3T00 A;  1ZEF A;  1ED9 A;  1SHN A;  1EW8 A;  3TX0 A;  3UN3 A;  1ELZ A;  2GLQ A;  1KH5 A;  1KHL A;  3UO0 A;  1Y6V A;  3UN5 A;  3OT9 A;  3UN2 A;  1ZEB A;  1N2K A;  2G9Y A;  3MK1 A;  3TWZ A;  3BDF A;  1E1Z P;  3T01 A;  3ED4 A;  1B8J A;  2QZU A;  1KH9 A;  1KHJ A;  1ALJ A;  3M8Y A;  1KH4 A;  3CMR A;  1E3C P;  1O99 A;  3IGY B;  1AUK A;  3IGZ B;  1N2L A;  2GA3 A;  2IFY A;  3SZZ A;  1KHK A;  3M7V A;  1ELY A;  3MK2 A;  1P49 A;  1KHN A;  3BDG A;  4FDI A;  1KH7 A;  3NVL A;  1E2S P;  1URA A;  1EJJ A;  1K7H A;  3DYC A;  1ELX A;  1AJC A;  1AJA A;  2ANH A;  3MK0 A;  1EQJ A;  1SHQ A;  1ED8 A;  1ANJ A;  1AJD A;  1O98 A;  3BDG B;  3SZY A;  1HJK A;  1EI6 A;  1FSU A;  1URB A; 
#chains in the KnotProt database with same CATH homology
 3BDH A;  3M8Z A;  1ALI A;  3M8W A;  1ANI A;  1AJB A;  4FDJ A;  3DPC A;  1ALK A;  1EW2 A;  1ZED A;  1HQA A;  1EW9 A;  1E33 P;  3UNY A;  1HDH A;  3T02 A;  1Y7A A;  3T00 A;  1ZEF A;  1ED9 A;  1SHN A;  1EW8 A;  3TX0 A;  3UN3 A;  1ELZ A;  2GLQ A;  1KH5 A;  1KHL A;  3UO0 A;  1Y6V A;  3UN5 A;  3OT9 A;  3UN2 A;  1ZEB A;  1N2K A;  2G9Y A;  3MK1 A;  3TWZ A;  3BDF A;  1E1Z P;  3T01 A;  3ED4 A;  1B8J A;  2QZU A;  1KH9 A;  1KHJ A;  1ALJ A;  3M8Y A;  1KH4 A;  3CMR A;  1E3C P;  1O99 A;  3IGY B;  1AUK A;  3IGZ B;  1N2L A;  2GA3 A;  2IFY A;  3SZZ A;  1KHK A;  3M7V A;  1ELY A;  3MK2 A;  1P49 A;  1KHN A;  3BDG A;  4FDI A;  1KH7 A;  3NVL A;  1E2S P;  1URA A;  1EJJ A;  1K7H A;  3DYC A;  1ELX A;  1AJC A;  1AJA A;  2ANH A;  3MK0 A;  1EQJ A;  1SHQ A;  1ED8 A;  1ANJ A;  1AJD A;  1O98 A;  3BDG B;  3SZY A;  1HJK A;  1EI6 A;  1FSU A;  1URB A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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