3BDGA

Crystal structure of wild-type/t155v mixed dimer of e. coli alkaline phosphatase
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 46-367 322 1-45 418-448 368-417 45 31 slipknot
Chain Sequence
PEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDAVPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASI------ANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGHTGSQL--------RIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 46-365 320 1-45 396-434 366-395 45 39 slipknot
view details
3.1 46-395 350 1-45 402-434 396-401 45 33 slipknot
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2.1 44-401 358 1-43 406-434 402-405 43 29 slipknot
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2.1 37-405 369 1-5, 407-434 6-36, 406-406 5 28 slipknot
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2.1 31-359 329 1-7, 366-434 8-30, 360-365 7 69 slipknot
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2.1 38-360 323 1-30, 366-434 31-37, 361-365 30 69 slipknot
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2.1 39-361 323 1-37, 366-434 38-38, 362-365 37 69 slipknot
sequence length 448
structure length 434
publication title The Active-Site Trimetallic Cluster of Alkaline Phosphatase is Lost Upon Isosteric Mutation at the Mg2+-Coordinating Residue Threonine-155
rcsb
molecule tags Hydrolase
molecule keywords Alkaline phosphatase
source organism Escherichia coli
missing residues 326-331, 403-410
total genus Genus: 159
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2007-11-14
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3bdgA00
1AUKA 1E2SP 1HQAA 1AJCA 3M8WA 3BDGB 2IFYA 3BDGA 3IGYB 1ED8A 1E33P 3UN5A 3BDFA 1Y7AA 1KHLA 1O98A 3UO0A 3CMRA 2GA3A 1E1ZP 3MK2A 1N2LA 1KHNA 1Y6VA 3T01A 3ED4A 3M8YA 1ALIA 3SZYA 1ALKA 4FDJA 3MK0A 1ZEDA 3NVLA 3BDHA 1URAA 1EI6A 3MK1A 3TWZA 1URBA 1AJBA 1ELYA 1ED9A 1ZEFA 1KH5A 3TX0A 1O99A 3IGZB 1EJJA 3T02A 1P49A 1KH4A 1HDHA 3M7VA 3T00A 3UNYA 1SHQA 1ALHA 3DYCA 3DPCA 1N2KA 1KH9A 2QZUA 2GLQA 1ZEBA 1EW2A 1ANIA 3SZZA 1K7HA 3UN3A 1HJKA 1ALJA 1E3CP 1EW9A 1ANJA 1FSUA 1ELXA 1ELZA 1SHNA 1EQJA 1AJAA 2G9YA 1EW8A 3M8ZA 1AJDA 1KH7A 1KHKA 1B8JA 3UN2A 1KHJA 4FDIA 2ANHA 3OT9A
chains in the KnotProt database with same CATH superfamily
1AUKA 1E2SP 1HQAA 1AJCA 3M8WA 3BDGB 2IFYA 3BDGA 3IGYB 1ED8A 1E33P 3UN5A 3BDFA 1Y7AA 1KHLA 1O98A 3UO0A 3CMRA 2GA3A 1E1ZP 3MK2A 1N2LA 1KHNA 1Y6VA 3T01A 3ED4A 3M8YA 1ALIA 3SZYA 1ALKA 4FDJA 3MK0A 1ZEDA 3NVLA 3BDHA 1URAA 1EI6A 3MK1A 3TWZA 1URBA 1AJBA 1ELYA 1ED9A 1ZEFA 1KH5A 3TX0A 1O99A 3IGZB 1EJJA 3T02A 1P49A 1KH4A 1HDHA 3M7VA 3T00A 3UNYA 1SHQA 1ALHA 3DYCA 3DPCA 1N2KA 1KH9A 2QZUA 2GLQA 1ZEBA 1EW2A 1ANIA 3SZZA 1K7HA 3UN3A 1HJKA 1ALJA 1E3CP 1EW9A 1ANJA 1FSUA 1ELXA 1ELZA 1SHNA 1EQJA 1AJAA 2G9YA 1EW8A 3M8ZA 1AJDA 1KH7A 1KHKA 1B8JA 3UN2A 1KHJA 4FDIA 2ANHA 3OT9A
chains in the KnotProt database with same CATH topology
1AUKA 1E2SP 1HQAA 1AJCA 3M8WA 3BDGB 2IFYA 3BDGA 3IGYB 1ED8A 1E33P 3UN5A 3BDFA 1Y7AA 1KHLA 1O98A 3UO0A 3CMRA 2GA3A 1E1ZP 3MK2A 1N2LA 1KHNA 1Y6VA 3T01A 3ED4A 3M8YA 1ALIA 3SZYA 1ALKA 4FDJA 3MK0A 1ZEDA 3NVLA 3BDHA 1URAA 1EI6A 3MK1A 3TWZA 1URBA 1AJBA 1ELYA 1ED9A 1ZEFA 1KH5A 3TX0A 1O99A 3IGZB 1EJJA 3T02A 1P49A 1KH4A 1HDHA 3M7VA 3T00A 3UNYA 1SHQA 1ALHA 3DYCA 3DPCA 1N2KA 1KH9A 2QZUA 2GLQA 1ZEBA 1EW2A 1ANIA 3SZZA 1K7HA 3UN3A 1HJKA 1ALJA 1E3CP 1EW9A 1ANJA 1FSUA 1ELXA 1ELZA 1SHNA 1EQJA 1AJAA 2G9YA 1EW8A 3M8ZA 1AJDA 1KH7A 1KHKA 1B8JA 3UN2A 1KHJA 4FDIA 2ANHA 3OT9A
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1AUK A;  1E2S P;  1HQA A;  1AJC A;  3M8W A;  3BDG B;  2IFY A;  3BDG A;  3IGY B;  1ED8 A;  1E33 P;  3UN5 A;  3BDF A;  1Y7A A;  1KHL A;  1O98 A;  3UO0 A;  3CMR A;  2GA3 A;  1E1Z P;  3MK2 A;  1N2L A;  1KHN A;  1Y6V A;  3T01 A;  3ED4 A;  3M8Y A;  1ALI A;  3SZY A;  1ALK A;  4FDJ A;  3MK0 A;  1ZED A;  3NVL A;  3BDH A;  1URA A;  1EI6 A;  3MK1 A;  3TWZ A;  1URB A;  1AJB A;  1ELY A;  1ED9 A;  1ZEF A;  1KH5 A;  3TX0 A;  1O99 A;  3IGZ B;  1EJJ A;  3T02 A;  1P49 A;  1KH4 A;  1HDH A;  3M7V A;  3T00 A;  3UNY A;  1SHQ A;  1ALH A;  3DYC A;  3DPC A;  1N2K A;  1KH9 A;  2QZU A;  2GLQ A;  1ZEB A;  1EW2 A;  1ANI A;  3SZZ A;  1K7H A;  3UN3 A;  1HJK A;  1ALJ A;  1E3C P;  1EW9 A;  1ANJ A;  1FSU A;  1ELX A;  1ELZ A;  1SHN A;  1EQJ A;  1AJA A;  2G9Y A;  1EW8 A;  3M8Z A;  1AJD A;  1KH7 A;  1KHK A;  1B8J A;  3UN2 A;  1KHJ A;  4FDI A;  2ANH A;  3OT9 A; 
#chains in the KnotProt database with same CATH topology
 1AUK A;  1E2S P;  1HQA A;  1AJC A;  3M8W A;  3BDG B;  2IFY A;  3BDG A;  3IGY B;  1ED8 A;  1E33 P;  3UN5 A;  3BDF A;  1Y7A A;  1KHL A;  1O98 A;  3UO0 A;  3CMR A;  2GA3 A;  1E1Z P;  3MK2 A;  1N2L A;  1KHN A;  1Y6V A;  3T01 A;  3ED4 A;  3M8Y A;  1ALI A;  3SZY A;  1ALK A;  4FDJ A;  3MK0 A;  1ZED A;  3NVL A;  3BDH A;  1URA A;  1EI6 A;  3MK1 A;  3TWZ A;  1URB A;  1AJB A;  1ELY A;  1ED9 A;  1ZEF A;  1KH5 A;  3TX0 A;  1O99 A;  3IGZ B;  1EJJ A;  3T02 A;  1P49 A;  1KH4 A;  1HDH A;  3M7V A;  3T00 A;  3UNY A;  1SHQ A;  1ALH A;  3DYC A;  3DPC A;  1N2K A;  1KH9 A;  2QZU A;  2GLQ A;  1ZEB A;  1EW2 A;  1ANI A;  3SZZ A;  1K7H A;  3UN3 A;  1HJK A;  1ALJ A;  1E3C P;  1EW9 A;  1ANJ A;  1FSU A;  1ELX A;  1ELZ A;  1SHN A;  1EQJ A;  1AJA A;  2G9Y A;  1EW8 A;  3M8Z A;  1AJD A;  1KH7 A;  1KHK A;  1B8J A;  3UN2 A;  1KHJ A;  4FDI A;  2ANH A;  3OT9 A; 
#chains in the KnotProt database with same CATH homology
 1AUK A;  1E2S P;  1HQA A;  1AJC A;  3M8W A;  3BDG B;  2IFY A;  3BDG A;  3IGY B;  1ED8 A;  1E33 P;  3UN5 A;  3BDF A;  1Y7A A;  1KHL A;  1O98 A;  3UO0 A;  3CMR A;  2GA3 A;  1E1Z P;  3MK2 A;  1N2L A;  1KHN A;  1Y6V A;  3T01 A;  3ED4 A;  3M8Y A;  1ALI A;  3SZY A;  1ALK A;  4FDJ A;  3MK0 A;  1ZED A;  3NVL A;  3BDH A;  1URA A;  1EI6 A;  3MK1 A;  3TWZ A;  1URB A;  1AJB A;  1ELY A;  1ED9 A;  1ZEF A;  1KH5 A;  3TX0 A;  1O99 A;  3IGZ B;  1EJJ A;  3T02 A;  1P49 A;  1KH4 A;  1HDH A;  3M7V A;  3T00 A;  3UNY A;  1SHQ A;  1ALH A;  3DYC A;  3DPC A;  1N2K A;  1KH9 A;  2QZU A;  2GLQ A;  1ZEB A;  1EW2 A;  1ANI A;  3SZZ A;  1K7H A;  3UN3 A;  1HJK A;  1ALJ A;  1E3C P;  1EW9 A;  1ANJ A;  1FSU A;  1ELX A;  1ELZ A;  1SHN A;  1EQJ A;  1AJA A;  2G9Y A;  1EW8 A;  3M8Z A;  1AJD A;  1KH7 A;  1KHK A;  1B8J A;  3UN2 A;  1KHJ A;  4FDI A;  2ANH A;  3OT9 A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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