1URBA

Alkaline phosphatase (n51mg)
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 43-366 324 1-42 416-446 367-415 42 31 slipknot
Chain Sequence
MPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGNGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 25-364 340 1-24 371-446 365-370 24 76 slipknot
view details
3.1 43-368 326 1-42 386-446 369-385 42 61 slipknot
view details
3.1 45-369 325 1-44 413-446 370-412 44 34 slipknot
view details
3.1 42-367 326 1-24, 369-446 25-41, 368-368 24 78 slipknot
view details
2.1 43-412 370 1-17, 418-446 18-42, 413-417 17 29 slipknot
sequence length 446
structure length 446
publication title Kinetic and structural consequences of replacing the aspartate bridge by asparagine in the catalytic metal triad of Escherichia coli alkaline phosphatase.
pubmed doi rcsb
molecule tags Alkaline phosphatase
molecule keywords ALKALINE PHOSPHATASE
source organism Escherichia coli
total genus Genus: 163
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 1996-02-03
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1urbA00
1HDHA 2IFYA 1KH5A 1O99A 1KHNA 1URAA 2GA3A 1ELXA 1AJAA 3BDGB 1EW2A 1Y7AA 1HJKA 1URBA 1KHKA 1AUKA 2QZUA 3UNYA 1HQAA 3IGZB 2GLQA 1EQJA 3UN3A 1N2LA 1FSUA 1EI6A 1ALHA 3UO0A 1P49A 3SZZA 3MK2A 3T00A 1ZEDA 4FDIA 3M7VA 3TWZA 1ELZA 3BDHA 3BDGA 1KH4A 1AJDA 1B8JA 1KHJA 1ED8A 3ED4A 3NVLA 3SZYA 1E1ZP 3DYCA 3M8WA 3CMRA 3T01A 1K7HA 1ED9A 1O98A 1ZEBA 3M8ZA 1EW8A 1ANJA 1KH7A 1N2KA 4FDJA 1Y6VA 3BDFA 1AJCA 3OT9A 1ELYA 1KH9A 1KHLA 3UN5A 1ZEFA 2G9YA 1EJJA 1E2SP 3MK0A 1ANIA 1E3CP 1ALIA 3MK1A 3T02A 1EW9A 3UN2A 3M8YA 1ALKA 3DPCA 1SHQA 3IGYB 1ALJA 1SHNA 2ANHA 3TX0A 1AJBA 1E33P
chains in the KnotProt database with same CATH superfamily
1HDHA 2IFYA 1KH5A 1O99A 1KHNA 1URAA 2GA3A 1ELXA 1AJAA 3BDGB 1EW2A 1Y7AA 1HJKA 1URBA 1KHKA 1AUKA 2QZUA 3UNYA 1HQAA 3IGZB 2GLQA 1EQJA 3UN3A 1N2LA 1FSUA 1EI6A 1ALHA 3UO0A 1P49A 3SZZA 3MK2A 3T00A 1ZEDA 4FDIA 3M7VA 3TWZA 1ELZA 3BDHA 3BDGA 1KH4A 1AJDA 1B8JA 1KHJA 1ED8A 3ED4A 3NVLA 3SZYA 1E1ZP 3DYCA 3M8WA 3CMRA 3T01A 1K7HA 1ED9A 1O98A 1ZEBA 3M8ZA 1EW8A 1ANJA 1KH7A 1N2KA 4FDJA 1Y6VA 3BDFA 1AJCA 3OT9A 1ELYA 1KH9A 1KHLA 3UN5A 1ZEFA 2G9YA 1EJJA 1E2SP 3MK0A 1ANIA 1E3CP 1ALIA 3MK1A 3T02A 1EW9A 3UN2A 3M8YA 1ALKA 3DPCA 1SHQA 3IGYB 1ALJA 1SHNA 2ANHA 3TX0A 1AJBA 1E33P
chains in the KnotProt database with same CATH topology
1HDHA 2IFYA 1KH5A 1O99A 1KHNA 1URAA 2GA3A 1ELXA 1AJAA 3BDGB 1EW2A 1Y7AA 1HJKA 1URBA 1KHKA 1AUKA 2QZUA 3UNYA 1HQAA 3IGZB 2GLQA 1EQJA 3UN3A 1N2LA 1FSUA 1EI6A 1ALHA 3UO0A 1P49A 3SZZA 3MK2A 3T00A 1ZEDA 4FDIA 3M7VA 3TWZA 1ELZA 3BDHA 3BDGA 1KH4A 1AJDA 1B8JA 1KHJA 1ED8A 3ED4A 3NVLA 3SZYA 1E1ZP 3DYCA 3M8WA 3CMRA 3T01A 1K7HA 1ED9A 1O98A 1ZEBA 3M8ZA 1EW8A 1ANJA 1KH7A 1N2KA 4FDJA 1Y6VA 3BDFA 1AJCA 3OT9A 1ELYA 1KH9A 1KHLA 3UN5A 1ZEFA 2G9YA 1EJJA 1E2SP 3MK0A 1ANIA 1E3CP 1ALIA 3MK1A 3T02A 1EW9A 3UN2A 3M8YA 1ALKA 3DPCA 1SHQA 3IGYB 1ALJA 1SHNA 2ANHA 3TX0A 1AJBA 1E33P
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1HDH A;  2IFY A;  1KH5 A;  1O99 A;  1KHN A;  1URA A;  2GA3 A;  1ELX A;  1AJA A;  3BDG B;  1EW2 A;  1Y7A A;  1HJK A;  1URB A;  1KHK A;  1AUK A;  2QZU A;  3UNY A;  1HQA A;  3IGZ B;  2GLQ A;  1EQJ A;  3UN3 A;  1N2L A;  1FSU A;  1EI6 A;  1ALH A;  3UO0 A;  1P49 A;  3SZZ A;  3MK2 A;  3T00 A;  1ZED A;  4FDI A;  3M7V A;  3TWZ A;  1ELZ A;  3BDH A;  3BDG A;  1KH4 A;  1AJD A;  1B8J A;  1KHJ A;  1ED8 A;  3ED4 A;  3NVL A;  3SZY A;  1E1Z P;  3DYC A;  3M8W A;  3CMR A;  3T01 A;  1K7H A;  1ED9 A;  1O98 A;  1ZEB A;  3M8Z A;  1EW8 A;  1ANJ A;  1KH7 A;  1N2K A;  4FDJ A;  1Y6V A;  3BDF A;  1AJC A;  3OT9 A;  1ELY A;  1KH9 A;  1KHL A;  3UN5 A;  1ZEF A;  2G9Y A;  1EJJ A;  1E2S P;  3MK0 A;  1ANI A;  1E3C P;  1ALI A;  3MK1 A;  3T02 A;  1EW9 A;  3UN2 A;  3M8Y A;  1ALK A;  3DPC A;  1SHQ A;  3IGY B;  1ALJ A;  1SHN A;  2ANH A;  3TX0 A;  1AJB A;  1E33 P; 
#chains in the KnotProt database with same CATH topology
 1HDH A;  2IFY A;  1KH5 A;  1O99 A;  1KHN A;  1URA A;  2GA3 A;  1ELX A;  1AJA A;  3BDG B;  1EW2 A;  1Y7A A;  1HJK A;  1URB A;  1KHK A;  1AUK A;  2QZU A;  3UNY A;  1HQA A;  3IGZ B;  2GLQ A;  1EQJ A;  3UN3 A;  1N2L A;  1FSU A;  1EI6 A;  1ALH A;  3UO0 A;  1P49 A;  3SZZ A;  3MK2 A;  3T00 A;  1ZED A;  4FDI A;  3M7V A;  3TWZ A;  1ELZ A;  3BDH A;  3BDG A;  1KH4 A;  1AJD A;  1B8J A;  1KHJ A;  1ED8 A;  3ED4 A;  3NVL A;  3SZY A;  1E1Z P;  3DYC A;  3M8W A;  3CMR A;  3T01 A;  1K7H A;  1ED9 A;  1O98 A;  1ZEB A;  3M8Z A;  1EW8 A;  1ANJ A;  1KH7 A;  1N2K A;  4FDJ A;  1Y6V A;  3BDF A;  1AJC A;  3OT9 A;  1ELY A;  1KH9 A;  1KHL A;  3UN5 A;  1ZEF A;  2G9Y A;  1EJJ A;  1E2S P;  3MK0 A;  1ANI A;  1E3C P;  1ALI A;  3MK1 A;  3T02 A;  1EW9 A;  3UN2 A;  3M8Y A;  1ALK A;  3DPC A;  1SHQ A;  3IGY B;  1ALJ A;  1SHN A;  2ANH A;  3TX0 A;  1AJB A;  1E33 P; 
#chains in the KnotProt database with same CATH homology
 1HDH A;  2IFY A;  1KH5 A;  1O99 A;  1KHN A;  1URA A;  2GA3 A;  1ELX A;  1AJA A;  3BDG B;  1EW2 A;  1Y7A A;  1HJK A;  1URB A;  1KHK A;  1AUK A;  2QZU A;  3UNY A;  1HQA A;  3IGZ B;  2GLQ A;  1EQJ A;  3UN3 A;  1N2L A;  1FSU A;  1EI6 A;  1ALH A;  3UO0 A;  1P49 A;  3SZZ A;  3MK2 A;  3T00 A;  1ZED A;  4FDI A;  3M7V A;  3TWZ A;  1ELZ A;  3BDH A;  3BDG A;  1KH4 A;  1AJD A;  1B8J A;  1KHJ A;  1ED8 A;  3ED4 A;  3NVL A;  3SZY A;  1E1Z P;  3DYC A;  3M8W A;  3CMR A;  3T01 A;  1K7H A;  1ED9 A;  1O98 A;  1ZEB A;  3M8Z A;  1EW8 A;  1ANJ A;  1KH7 A;  1N2K A;  4FDJ A;  1Y6V A;  3BDF A;  1AJC A;  3OT9 A;  1ELY A;  1KH9 A;  1KHL A;  3UN5 A;  1ZEF A;  2G9Y A;  1EJJ A;  1E2S P;  3MK0 A;  1ANI A;  1E3C P;  1ALI A;  3MK1 A;  3T02 A;  1EW9 A;  3UN2 A;  3M8Y A;  1ALK A;  3DPC A;  1SHQ A;  3IGY B;  1ALJ A;  1SHN A;  2ANH A;  3TX0 A;  1AJB A;  1E33 P; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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