1HJKA

Alkaline phosphatase mutant h331q
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 46-369 324 1-45 419-449 370-418 45 31 slipknot
Chain Sequence
TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDQAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 46-370 325 1-45 389-449 371-388 45 61 slipknot
view details
3.1 47-371 325 1-46 415-449 372-414 46 35 slipknot
view details
2.1 45-414 370 1-44 421-449 415-420 44 29 slipknot
view details
2.1 24-366 343 1-6, 371-449 7-23, 367-370 6 79 slipknot
view details
2.1 41-366 326 1-23, 371-449 24-40, 367-370 23 79 slipknot
sequence length 449
structure length 449
publication title Trapping and visualization of a covalent enzyme-phosphate intermediate.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords ALKALINE PHOSPHATASE
source organism Escherichia coli
total genus Genus: 152
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 1997-05-30
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1hjkA00
1AJAA 1KHJA 3SZZA 3M7VA 1URBA 1EW8A 1EQJA 1EI6A 3M8WA 1HDHA 3UN3A 4FDIA 1ELZA 1EW9A 1AJCA 3MK1A 1ANJA 1Y6VA 3T02A 2GA3A 3UO0A 1KHKA 1E2SP 1N2KA 2ANHA 1KH7A 3SZYA 1O99A 1P49A 3M8YA 1KH5A 3BDGB 1EJJA 1ALJA 1EW2A 3OT9A 3BDFA 1ED8A 3T00A 1KH9A 1ED9A 2QZUA 1KHLA 1HQAA 1E33P 3BDHA 3T01A 1ELXA 3BDGA 1ZEDA 1B8JA 1AUKA 1KHNA 1SHQA 3ED4A 3IGZB 1K7HA 1HJKA 3TWZA 4FDJA 3UN5A 3DYCA 1ZEBA 1N2LA 1O98A 1ELYA 3CMRA 1AJBA 3UN2A 2GLQA 1URAA 1ZEFA 1ALKA 1FSUA 2G9YA 1ANIA 1ALIA 3MK0A 2IFYA 1Y7AA 3IGYB 3NVLA 3TX0A 1E3CP 3M8ZA 1E1ZP 1SHNA 3MK2A 1AJDA 3DPCA 3UNYA 1KH4A
chains in the KnotProt database with same CATH superfamily
1AJAA 1KHJA 3SZZA 3M7VA 1URBA 1EW8A 1EQJA 1EI6A 3M8WA 1HDHA 3UN3A 4FDIA 1ELZA 1EW9A 1AJCA 3MK1A 1ANJA 1Y6VA 3T02A 2GA3A 3UO0A 1KHKA 1E2SP 1N2KA 2ANHA 1KH7A 3SZYA 1O99A 1P49A 3M8YA 1KH5A 3BDGB 1EJJA 1ALJA 1EW2A 3OT9A 3BDFA 1ED8A 3T00A 1KH9A 1ED9A 2QZUA 1KHLA 1HQAA 1E33P 3BDHA 3T01A 1ELXA 3BDGA 1ZEDA 1B8JA 1AUKA 1KHNA 1SHQA 3ED4A 3IGZB 1K7HA 1HJKA 3TWZA 4FDJA 3UN5A 3DYCA 1ZEBA 1N2LA 1O98A 1ELYA 3CMRA 1AJBA 3UN2A 2GLQA 1URAA 1ZEFA 1ALKA 1FSUA 2G9YA 1ANIA 1ALIA 3MK0A 2IFYA 1Y7AA 3IGYB 3NVLA 3TX0A 1E3CP 3M8ZA 1E1ZP 1SHNA 3MK2A 1AJDA 3DPCA 3UNYA 1KH4A
chains in the KnotProt database with same CATH topology
1AJAA 1KHJA 3SZZA 3M7VA 1URBA 1EW8A 1EQJA 1EI6A 3M8WA 1HDHA 3UN3A 4FDIA 1ELZA 1EW9A 1AJCA 3MK1A 1ANJA 1Y6VA 3T02A 2GA3A 3UO0A 1KHKA 1E2SP 1N2KA 2ANHA 1KH7A 3SZYA 1O99A 1P49A 3M8YA 1KH5A 3BDGB 1EJJA 1ALJA 1EW2A 3OT9A 3BDFA 1ED8A 3T00A 1KH9A 1ED9A 2QZUA 1KHLA 1HQAA 1E33P 3BDHA 3T01A 1ELXA 3BDGA 1ZEDA 1B8JA 1AUKA 1KHNA 1SHQA 3ED4A 3IGZB 1K7HA 1HJKA 3TWZA 4FDJA 3UN5A 3DYCA 1ZEBA 1N2LA 1O98A 1ELYA 3CMRA 1AJBA 3UN2A 2GLQA 1URAA 1ZEFA 1ALKA 1FSUA 2G9YA 1ANIA 1ALIA 3MK0A 2IFYA 1Y7AA 3IGYB 3NVLA 3TX0A 1E3CP 3M8ZA 1E1ZP 1SHNA 3MK2A 1AJDA 3DPCA 3UNYA 1KH4A
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1AJA A;  1KHJ A;  3SZZ A;  3M7V A;  1URB A;  1EW8 A;  1EQJ A;  1EI6 A;  3M8W A;  1HDH A;  3UN3 A;  4FDI A;  1ELZ A;  1EW9 A;  1AJC A;  3MK1 A;  1ANJ A;  1Y6V A;  3T02 A;  2GA3 A;  3UO0 A;  1KHK A;  1E2S P;  1N2K A;  2ANH A;  1KH7 A;  3SZY A;  1O99 A;  1P49 A;  3M8Y A;  1KH5 A;  3BDG B;  1EJJ A;  1ALJ A;  1EW2 A;  3OT9 A;  3BDF A;  1ED8 A;  3T00 A;  1KH9 A;  1ED9 A;  2QZU A;  1KHL A;  1HQA A;  1E33 P;  3BDH A;  3T01 A;  1ELX A;  3BDG A;  1ZED A;  1B8J A;  1AUK A;  1KHN A;  1SHQ A;  3ED4 A;  3IGZ B;  1K7H A;  1HJK A;  3TWZ A;  4FDJ A;  3UN5 A;  3DYC A;  1ZEB A;  1N2L A;  1O98 A;  1ELY A;  3CMR A;  1AJB A;  3UN2 A;  2GLQ A;  1URA A;  1ZEF A;  1ALK A;  1FSU A;  2G9Y A;  1ANI A;  1ALI A;  3MK0 A;  2IFY A;  1Y7A A;  3IGY B;  3NVL A;  3TX0 A;  1E3C P;  3M8Z A;  1E1Z P;  1SHN A;  3MK2 A;  1AJD A;  3DPC A;  3UNY A;  1KH4 A; 
#chains in the KnotProt database with same CATH topology
 1AJA A;  1KHJ A;  3SZZ A;  3M7V A;  1URB A;  1EW8 A;  1EQJ A;  1EI6 A;  3M8W A;  1HDH A;  3UN3 A;  4FDI A;  1ELZ A;  1EW9 A;  1AJC A;  3MK1 A;  1ANJ A;  1Y6V A;  3T02 A;  2GA3 A;  3UO0 A;  1KHK A;  1E2S P;  1N2K A;  2ANH A;  1KH7 A;  3SZY A;  1O99 A;  1P49 A;  3M8Y A;  1KH5 A;  3BDG B;  1EJJ A;  1ALJ A;  1EW2 A;  3OT9 A;  3BDF A;  1ED8 A;  3T00 A;  1KH9 A;  1ED9 A;  2QZU A;  1KHL A;  1HQA A;  1E33 P;  3BDH A;  3T01 A;  1ELX A;  3BDG A;  1ZED A;  1B8J A;  1AUK A;  1KHN A;  1SHQ A;  3ED4 A;  3IGZ B;  1K7H A;  1HJK A;  3TWZ A;  4FDJ A;  3UN5 A;  3DYC A;  1ZEB A;  1N2L A;  1O98 A;  1ELY A;  3CMR A;  1AJB A;  3UN2 A;  2GLQ A;  1URA A;  1ZEF A;  1ALK A;  1FSU A;  2G9Y A;  1ANI A;  1ALI A;  3MK0 A;  2IFY A;  1Y7A A;  3IGY B;  3NVL A;  3TX0 A;  1E3C P;  3M8Z A;  1E1Z P;  1SHN A;  3MK2 A;  1AJD A;  3DPC A;  3UNY A;  1KH4 A; 
#chains in the KnotProt database with same CATH homology
 1AJA A;  1KHJ A;  3SZZ A;  3M7V A;  1URB A;  1EW8 A;  1EQJ A;  1EI6 A;  3M8W A;  1HDH A;  3UN3 A;  4FDI A;  1ELZ A;  1EW9 A;  1AJC A;  3MK1 A;  1ANJ A;  1Y6V A;  3T02 A;  2GA3 A;  3UO0 A;  1KHK A;  1E2S P;  1N2K A;  2ANH A;  1KH7 A;  3SZY A;  1O99 A;  1P49 A;  3M8Y A;  1KH5 A;  3BDG B;  1EJJ A;  1ALJ A;  1EW2 A;  3OT9 A;  3BDF A;  1ED8 A;  3T00 A;  1KH9 A;  1ED9 A;  2QZU A;  1KHL A;  1HQA A;  1E33 P;  3BDH A;  3T01 A;  1ELX A;  3BDG A;  1ZED A;  1B8J A;  1AUK A;  1KHN A;  1SHQ A;  3ED4 A;  3IGZ B;  1K7H A;  1HJK A;  3TWZ A;  4FDJ A;  3UN5 A;  3DYC A;  1ZEB A;  1N2L A;  1O98 A;  1ELY A;  3CMR A;  1AJB A;  3UN2 A;  2GLQ A;  1URA A;  1ZEF A;  1ALK A;  1FSU A;  2G9Y A;  1ANI A;  1ALI A;  3MK0 A;  2IFY A;  1Y7A A;  3IGY B;  3NVL A;  3TX0 A;  1E3C P;  3M8Z A;  1E1Z P;  1SHN A;  3MK2 A;  1AJD A;  3DPC A;  3UNY A;  1KH4 A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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