3DPCA

Structure of e.coli alkaline phosphatase mutant in complex with a phosphorylated peptide
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 46-366 321 1-45 418-449 367-417 45 32 slipknot
Chain Sequence
PEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDLAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLKH
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 43-367 325 1-42 375-449 368-374 42 75 slipknot
view details
3.1 46-372 327 1-45 408-449 373-407 45 42 slipknot
view details
3.1 44-407 364 1-43 411-449 408-410 43 39 slipknot
view details
3.1 44-411 368 1-43 417-449 412-416 43 33 slipknot
sequence length 449
structure length 449
publication title Development of a universal phosphorylated peptide-binding protein for simultaneous assay of kinases
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Alkaline phosphatase
source organism Escherichia coli
total genus Genus: 147
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2008-07-07
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3dpcA00
1ED9A 1N2LA 1E1ZP 1FSUA 3UO0A 3BDGB 1AUKA 3BDHA 1HJKA 3M8ZA 3MK1A 1ANJA 1E2SP 3TX0A 1ALKA 1HDHA 1KH7A 3T00A 1O99A 1ZEBA 3UNYA 1E33P 3BDFA 1ANIA 3M7VA 1O98A 1SHNA 3SZYA 3SZZA 3TWZA 3UN5A 3DPCA 3T01A 2G9YA 1AJAA 1URAA 1ZEDA 1EQJA 2GLQA 1P49A 1KH9A 1AJCA 1ALIA 1E3CP 1EW2A 1KH4A 3MK2A 1ZEFA 1AJBA 3IGYB 1ALJA 1Y6VA 1EI6A 1ELZA 3CMRA 3OT9A 1KHLA 4FDIA 1KHKA 1SHQA 4FDJA 2IFYA 3NVLA 1AJDA 1ELXA 2GA3A 1KHJA 3ED4A 3UN2A 2QZUA 3M8WA 3UN3A 1EJJA 1HQAA 1B8JA 3DYCA 1Y7AA 1N2KA 1K7HA 1EW8A 3M8YA 1EW9A 1ELYA 1KH5A 3MK0A 1URBA 3T02A 1ED8A 3IGZB 2ANHA 3BDGA 1KHNA
chains in the KnotProt database with same CATH superfamily
1ED9A 1N2LA 1E1ZP 1FSUA 3UO0A 3BDGB 1AUKA 3BDHA 1HJKA 3M8ZA 3MK1A 1ANJA 1E2SP 3TX0A 1ALKA 1HDHA 1KH7A 3T00A 1O99A 1ZEBA 3UNYA 1E33P 3BDFA 1ANIA 3M7VA 1O98A 1SHNA 3SZYA 3SZZA 3TWZA 3UN5A 3DPCA 3T01A 2G9YA 1AJAA 1URAA 1ZEDA 1EQJA 2GLQA 1P49A 1KH9A 1AJCA 1ALIA 1E3CP 1EW2A 1KH4A 3MK2A 1ZEFA 1AJBA 3IGYB 1ALJA 1Y6VA 1EI6A 1ELZA 3CMRA 3OT9A 1KHLA 4FDIA 1KHKA 1SHQA 4FDJA 2IFYA 3NVLA 1AJDA 1ELXA 2GA3A 1KHJA 3ED4A 3UN2A 2QZUA 3M8WA 3UN3A 1EJJA 1HQAA 1B8JA 3DYCA 1Y7AA 1N2KA 1K7HA 1EW8A 3M8YA 1EW9A 1ELYA 1KH5A 3MK0A 1URBA 3T02A 1ED8A 3IGZB 2ANHA 3BDGA 1KHNA
chains in the KnotProt database with same CATH topology
1ED9A 1N2LA 1E1ZP 1FSUA 3UO0A 3BDGB 1AUKA 3BDHA 1HJKA 3M8ZA 3MK1A 1ANJA 1E2SP 3TX0A 1ALKA 1HDHA 1KH7A 3T00A 1O99A 1ZEBA 3UNYA 1E33P 3BDFA 1ANIA 3M7VA 1O98A 1SHNA 3SZYA 3SZZA 3TWZA 3UN5A 3DPCA 3T01A 2G9YA 1AJAA 1URAA 1ZEDA 1EQJA 2GLQA 1P49A 1KH9A 1AJCA 1ALIA 1E3CP 1EW2A 1KH4A 3MK2A 1ZEFA 1AJBA 3IGYB 1ALJA 1Y6VA 1EI6A 1ELZA 3CMRA 3OT9A 1KHLA 4FDIA 1KHKA 1SHQA 4FDJA 2IFYA 3NVLA 1AJDA 1ELXA 2GA3A 1KHJA 3ED4A 3UN2A 2QZUA 3M8WA 3UN3A 1EJJA 1HQAA 1B8JA 3DYCA 1Y7AA 1N2KA 1K7HA 1EW8A 3M8YA 1EW9A 1ELYA 1KH5A 3MK0A 1URBA 3T02A 1ED8A 3IGZB 2ANHA 3BDGA 1KHNA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1ED9 A;  1N2L A;  1E1Z P;  1FSU A;  3UO0 A;  3BDG B;  1AUK A;  3BDH A;  1HJK A;  3M8Z A;  3MK1 A;  1ANJ A;  1E2S P;  3TX0 A;  1ALK A;  1HDH A;  1KH7 A;  3T00 A;  1O99 A;  1ZEB A;  3UNY A;  1E33 P;  3BDF A;  1ANI A;  3M7V A;  1O98 A;  1SHN A;  3SZY A;  3SZZ A;  3TWZ A;  3UN5 A;  3DPC A;  3T01 A;  2G9Y A;  1AJA A;  1URA A;  1ZED A;  1EQJ A;  2GLQ A;  1P49 A;  1KH9 A;  1AJC A;  1ALI A;  1E3C P;  1EW2 A;  1KH4 A;  3MK2 A;  1ZEF A;  1AJB A;  3IGY B;  1ALJ A;  1Y6V A;  1EI6 A;  1ELZ A;  3CMR A;  3OT9 A;  1KHL A;  4FDI A;  1KHK A;  1SHQ A;  4FDJ A;  2IFY A;  3NVL A;  1AJD A;  1ELX A;  2GA3 A;  1KHJ A;  3ED4 A;  3UN2 A;  2QZU A;  3M8W A;  3UN3 A;  1EJJ A;  1HQA A;  1B8J A;  3DYC A;  1Y7A A;  1N2K A;  1K7H A;  1EW8 A;  3M8Y A;  1EW9 A;  1ELY A;  1KH5 A;  3MK0 A;  1URB A;  3T02 A;  1ED8 A;  3IGZ B;  2ANH A;  3BDG A;  1KHN A; 
#chains in the KnotProt database with same CATH topology
 1ED9 A;  1N2L A;  1E1Z P;  1FSU A;  3UO0 A;  3BDG B;  1AUK A;  3BDH A;  1HJK A;  3M8Z A;  3MK1 A;  1ANJ A;  1E2S P;  3TX0 A;  1ALK A;  1HDH A;  1KH7 A;  3T00 A;  1O99 A;  1ZEB A;  3UNY A;  1E33 P;  3BDF A;  1ANI A;  3M7V A;  1O98 A;  1SHN A;  3SZY A;  3SZZ A;  3TWZ A;  3UN5 A;  3DPC A;  3T01 A;  2G9Y A;  1AJA A;  1URA A;  1ZED A;  1EQJ A;  2GLQ A;  1P49 A;  1KH9 A;  1AJC A;  1ALI A;  1E3C P;  1EW2 A;  1KH4 A;  3MK2 A;  1ZEF A;  1AJB A;  3IGY B;  1ALJ A;  1Y6V A;  1EI6 A;  1ELZ A;  3CMR A;  3OT9 A;  1KHL A;  4FDI A;  1KHK A;  1SHQ A;  4FDJ A;  2IFY A;  3NVL A;  1AJD A;  1ELX A;  2GA3 A;  1KHJ A;  3ED4 A;  3UN2 A;  2QZU A;  3M8W A;  3UN3 A;  1EJJ A;  1HQA A;  1B8J A;  3DYC A;  1Y7A A;  1N2K A;  1K7H A;  1EW8 A;  3M8Y A;  1EW9 A;  1ELY A;  1KH5 A;  3MK0 A;  1URB A;  3T02 A;  1ED8 A;  3IGZ B;  2ANH A;  3BDG A;  1KHN A; 
#chains in the KnotProt database with same CATH homology
 1ED9 A;  1N2L A;  1E1Z P;  1FSU A;  3UO0 A;  3BDG B;  1AUK A;  3BDH A;  1HJK A;  3M8Z A;  3MK1 A;  1ANJ A;  1E2S P;  3TX0 A;  1ALK A;  1HDH A;  1KH7 A;  3T00 A;  1O99 A;  1ZEB A;  3UNY A;  1E33 P;  3BDF A;  1ANI A;  3M7V A;  1O98 A;  1SHN A;  3SZY A;  3SZZ A;  3TWZ A;  3UN5 A;  3DPC A;  3T01 A;  2G9Y A;  1AJA A;  1URA A;  1ZED A;  1EQJ A;  2GLQ A;  1P49 A;  1KH9 A;  1AJC A;  1ALI A;  1E3C P;  1EW2 A;  1KH4 A;  3MK2 A;  1ZEF A;  1AJB A;  3IGY B;  1ALJ A;  1Y6V A;  1EI6 A;  1ELZ A;  3CMR A;  3OT9 A;  1KHL A;  4FDI A;  1KHK A;  1SHQ A;  4FDJ A;  2IFY A;  3NVL A;  1AJD A;  1ELX A;  2GA3 A;  1KHJ A;  3ED4 A;  3UN2 A;  2QZU A;  3M8W A;  3UN3 A;  1EJJ A;  1HQA A;  1B8J A;  3DYC A;  1Y7A A;  1N2K A;  1K7H A;  1EW8 A;  3M8Y A;  1EW9 A;  1ELY A;  1KH5 A;  3MK0 A;  1URB A;  3T02 A;  1ED8 A;  3IGZ B;  2ANH A;  3BDG A;  1KHN A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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