1AUK | KnotProt

Genus: 154

Slipknot S +3₁

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setting document base to "https://knotprot.cent.uw.edu.pl/view/1auk/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

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APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

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Help Knotting data interpretation Full screen

					Knot core range	Knot core length	Knot tails range	Slipknot tails range	Slipknot loops range	N-end length	C-end length	Type
view details				+3₁	7-263	257	1-6	294-485	264-293	6	192	slipknot

Chain Sequence

RPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLXTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIPLLANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDGFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTADPACHASSSLTAHEPPLLYDLSKDPGENYNLLG----ATPEVLQALKQLQLLKAQLDAAVTFGPSQVARGEDPALQICCHPGCTPRPACCHCP

Whole chain analysis

Help Knotoid data interpretation Full screen

Subchain analysis

Knotoid cutoff: 0.5

Knotoid matrix content: 1

loadScript /static/js/j2s/core/package.js

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Jmol JavaScript applet jmolApplet0__283345190082867__ initializing

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AppletRegistry.checkIn(jmolApplet0__283345190082867__)

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Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

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Jmol getValue emulate null

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Jmol getValue APPLETREADYCallback Jmol._readyCallback

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callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

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Viewer cachePut cache://localLOAD_/static/knot_data/1auk/A/1auk_A.pdb.gz

Viewer cachePut https://knotprot.cent.uw.edu.pl/static/knot_data/1auk/A/1auk_A.pdb.gz

FileManager.getAtomSetCollectionFromFile(/static/knot_data/1auk/A/1auk_A.pdb.gz)

The Resolver thinks Pdb

loadScript /static/js/j2s/core/corebio.z.js

Time for openFile(/static/knot_data/1auk/A/1auk_A.pdb.gz): 268 ms

reading 481 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

481 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 95 ms

Adding embedded #jmolscript: select ({0:480});backbone only;select *;

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Script completed

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Viewer cachePut cache://localLOAD_/static/knot_data/1auk/A/1auk_A.pdb.gz

Viewer cachePut https://knotprot.cent.uw.edu.pl/static/knot_data/1auk/A/1auk_A.pdb.gz

Help Knotoid subchains data interpretation Full screen

		Knot core range	Knot core length	Knot tails range	Slipknot tails range	Slipknot loops range	N-end length	C-end length	Type
view details	3.1	7-265	259	1-6	275-481	266-274	6	207	slipknot
view details	2.1	6-275	270	1-5	292-481	276-291	5	190	slipknot
view details	2.1	8-281	274		1-5, 292-481	6-7, 282-291	5	190	slipknot

sequence length	485
structure length	481
publication title	Crystal structure of human arylsulfatase A: the aldehyde function and the metal ion at the active site suggest a novel mechanism for sulfate ester hydrolysis. pubmed doi rcsb
molecule tags	Hydrolase
molecule keywords	ARYLSULFATASE A
source organism	Homo sapiens
missing residues	426-429
total genus	Genus: 154
ec nomenclature	ec 3.1.6.8: Cerebroside-sulfatase.
pdb deposition date	1997-08-29
KnotProt deposition date	2014-07-31

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00884	Sulfatase	Sulfatase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.1120.10	Alpha Beta	2-Layer Sandwich	Arylsulfatase, C-terminal domain	Arylsulfatase, C-terminal domain	1aukA02
3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	1aukA01

3BDGA 1EJJA 1EW2A 2G9YA 1O98A 1ED8A 1ANJA 1ELXA 3MK0A 1FSUA 3T00A 1E33P 1SHQA 3UN2A 1HDHA 1Y7AA 1KHKA 3DPCA 3UN5A 3ED4A 2IFYA 3UO0A 1E3CP 3IGZB 1HJKA 3TWZA 1AJDA 1AJBA 1E1ZP 3T02A 1EW8A 3MK1A 1KH4A 1EI6A 3NVLA 4FDIA 2ANHA 3SZYA 4FDJA 3CMRA 3DYCA 2QZUA 1KHNA 1ALJA 1ELZA 3M8ZA 1Y6VA 1AJCA 1ALIA 3IGYB 3SZZA 2GA3A 1P49A 1KHLA 1URAA 1AJAA 1KH7A 1E2SP 3BDHA 3TX0A 1K7HA 1URBA 1N2KA 1KH5A 1EQJA 1ZEDA 1ZEBA 1ANIA 3M8WA 1EW9A 1ELYA 3OT9A 1HQAA 1B8JA 3T01A 3M8YA 1KH9A 1SHNA 3BDFA 1ZEFA 3UN3A 1ED9A 1ALKA 3UNYA 1N2LA 1O99A 1AUKA 3M7VA 3BDGB 3MK2A 1KHJA 2GLQA
chains in the KnotProt database with same CATH superfamily

#chains in the KnotProt database with same CATH superfamily
 3BDG A;  1EJJ A;  1EW2 A;  2G9Y A;  1O98 A;  1ED8 A;  1ANJ A;  1ELX A;  3MK0 A;  1FSU A;  3T00 A;  1E33 P;  1SHQ A;  3UN2 A;  1HDH A;  1Y7A A;  1KHK A;  3DPC A;  3UN5 A;  3ED4 A;  2IFY A;  3UO0 A;  1E3C P;  3IGZ B;  1HJK A;  3TWZ A;  1AJD A;  1AJB A;  1E1Z P;  3T02 A;  1EW8 A;  3MK1 A;  1KH4 A;  1EI6 A;  3NVL A;  4FDI A;  2ANH A;  3SZY A;  4FDJ A;  3CMR A;  3DYC A;  2QZU A;  1KHN A;  1ALJ A;  1ELZ A;  3M8Z A;  1Y6V A;  1AJC A;  1ALI A;  3IGY B;  3SZZ A;  2GA3 A;  1P49 A;  1KHL A;  1URA A;  1AJA A;  1KH7 A;  1E2S P;  3BDH A;  3TX0 A;  1K7H A;  1URB A;  1N2K A;  1KH5 A;  1EQJ A;  1ZED A;  1ZEB A;  1ANI A;  3M8W A;  1EW9 A;  1ELY A;  3OT9 A;  1HQA A;  1B8J A;  3T01 A;  3M8Y A;  1KH9 A;  1SHN A;  3BDF A;  1ZEF A;  3UN3 A;  1ED9 A;  1ALK A;  3UNY A;  1N2L A;  1O99 A;  1AUK A;  3M7V A;  3BDG B;  3MK2 A;  1KHJ A;  2GLQ A; 
#chains in the KnotProt database with same CATH topology
 3BDG A;  1EJJ A;  1EW2 A;  2G9Y A;  1O98 A;  1ED8 A;  1ANJ A;  1ELX A;  3MK0 A;  1FSU A;  3T00 A;  1E33 P;  1SHQ A;  3UN2 A;  1HDH A;  1Y7A A;  1KHK A;  3DPC A;  3UN5 A;  3ED4 A;  2IFY A;  3UO0 A;  1E3C P;  3IGZ B;  1HJK A;  3TWZ A;  1AJD A;  1AJB A;  1E1Z P;  3T02 A;  1EW8 A;  3MK1 A;  1KH4 A;  1EI6 A;  3NVL A;  4FDI A;  2ANH A;  3SZY A;  4FDJ A;  3CMR A;  3DYC A;  2QZU A;  1KHN A;  1ALJ A;  1ELZ A;  3M8Z A;  1Y6V A;  1AJC A;  1ALI A;  3IGY B;  3SZZ A;  2GA3 A;  1P49 A;  1KHL A;  1URA A;  1AJA A;  1KH7 A;  1E2S P;  3BDH A;  3TX0 A;  1K7H A;  1URB A;  1N2K A;  1KH5 A;  1EQJ A;  1ZED A;  1ZEB A;  1ANI A;  3M8W A;  1EW9 A;  1ELY A;  3OT9 A;  1HQA A;  1B8J A;  3T01 A;  3M8Y A;  1KH9 A;  1SHN A;  3BDF A;  1ZEF A;  3UN3 A;  1ED9 A;  1ALK A;  3UNY A;  1N2L A;  1O99 A;  1AUK A;  3M7V A;  3BDG B;  3MK2 A;  1KHJ A;  2GLQ A; 
#chains in the KnotProt database with same CATH homology
 3BDG A;  1EJJ A;  1EW2 A;  2G9Y A;  1O98 A;  1ED8 A;  1ANJ A;  1ELX A;  3MK0 A;  1FSU A;  3T00 A;  1E33 P;  1SHQ A;  3UN2 A;  1HDH A;  1Y7A A;  1KHK A;  3DPC A;  3UN5 A;  3ED4 A;  2IFY A;  3UO0 A;  1E3C P;  3IGZ B;  1HJK A;  3TWZ A;  1AJD A;  1AJB A;  1E1Z P;  3T02 A;  1EW8 A;  3MK1 A;  1KH4 A;  1EI6 A;  3NVL A;  4FDI A;  2ANH A;  3SZY A;  4FDJ A;  3CMR A;  3DYC A;  2QZU A;  1KHN A;  1ALJ A;  1ELZ A;  3M8Z A;  1Y6V A;  1AJC A;  1ALI A;  3IGY B;  3SZZ A;  2GA3 A;  1P49 A;  1KHL A;  1URA A;  1AJA A;  1KH7 A;  1E2S P;  3BDH A;  3TX0 A;  1K7H A;  1URB A;  1N2K A;  1KH5 A;  1EQJ A;  1ZED A;  1ZEB A;  1ANI A;  3M8W A;  1EW9 A;  1ELY A;  3OT9 A;  1HQA A;  1B8J A;  3T01 A;  3M8Y A;  1KH9 A;  1SHN A;  3BDF A;  1ZEF A;  3UN3 A;  1ED9 A;  1ALK A;  3UNY A;  1N2L A;  1O99 A;  1AUK A;  3M7V A;  3BDG B;  3MK2 A;  1KHJ A;  2GLQ A;

1E1ZP 1E2SP 1E33P 1E3CP 1N2KA 1N2LA
similar chains in the KnotProt database (40% sequence similarity)

None
similar chains in the pdb database (40% sequence similarity)

#similar chains in the KnotProt database (40% sequence similarity)
1E1Z P; 1E2S P; 1E33 P; 1E3C P; 1N2K A; 1N2L A; 
#similar chains, but unknotted

#similar chains in the pdb database (40% sequence similarity)

1AUKA

Slipknot S +31

Chain Sequence

pfam database annotations

Slipknot S +3₁