1ED9A

Structure of e. coli alkaline phosphatase without the inorganic phosphate at 1.75a resolution
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 46-369 324 1-45 419-449 370-418 45 31 slipknot
Chain Sequence
TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 47-371 325 1-46 417-449 372-416 46 33 slipknot
view details
2.1 45-416 372 1-44 421-449 417-420 44 29 slipknot
view details
2.1 24-367 344 1-11, 372-449 12-23, 368-371 11 78 slipknot
view details
3.1 37-368 332 1-24, 372-449 25-36, 369-371 24 78 slipknot
view details
2.1 43-366 324 1-26, 372-449 27-42, 367-371 26 78 slipknot
sequence length 449
structure length 449
publication title A revised mechanism for the alkaline phosphatase reaction involving three metal ions.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords ALKALINE PHOSPHATASE
source organism Escherichia coli
total genus Genus: 167
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2000-01-27
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1ed9A00
4FDJA 1AJBA 1HDHA 1SHQA 1HJKA 1KHNA 1K7HA 3M8WA 3BDGA 3UN2A 1E3CP 1ED8A 3OT9A 1EW8A 1ELYA 3UO0A 1EI6A 3IGYB 3MK0A 3BDHA 3UN5A 1ED9A 1N2LA 1URAA 1SHNA 3TX0A 1B8JA 1E2SP 1ALJA 1Y7AA 1ELXA 1KH7A 1ZEFA 1HQAA 1Y6VA 2G9YA 3M8ZA 3NVLA 1EQJA 2GA3A 1ALIA 1FSUA 3TWZA 1KHKA 3BDFA 1ANIA 3ED4A 3UN3A 3BDGB 3MK1A 3DPCA 1O99A 3T00A 1N2KA 1ANJA 3DYCA 1EW2A 1O98A 1ELZA 3SZZA 1AJDA 3T02A 1URBA 1AJAA 2ANHA 1KH4A 3CMRA 3MK2A 1KH9A 2IFYA 1E33P 2QZUA 3M7VA 2GLQA 1KH5A 3IGZB 3SZYA 1KHLA 3M8YA 3T01A 1EW9A 3UNYA 1ALKA 1KHJA 1P49A 1ZEDA 1ZEBA 1AUKA 1AJCA 1EJJA 4FDIA 1ALHA 1E1ZP
chains in the KnotProt database with same CATH superfamily
4FDJA 1AJBA 1HDHA 1SHQA 1HJKA 1KHNA 1K7HA 3M8WA 3BDGA 3UN2A 1E3CP 1ED8A 3OT9A 1EW8A 1ELYA 3UO0A 1EI6A 3IGYB 3MK0A 3BDHA 3UN5A 1ED9A 1N2LA 1URAA 1SHNA 3TX0A 1B8JA 1E2SP 1ALJA 1Y7AA 1ELXA 1KH7A 1ZEFA 1HQAA 1Y6VA 2G9YA 3M8ZA 3NVLA 1EQJA 2GA3A 1ALIA 1FSUA 3TWZA 1KHKA 3BDFA 1ANIA 3ED4A 3UN3A 3BDGB 3MK1A 3DPCA 1O99A 3T00A 1N2KA 1ANJA 3DYCA 1EW2A 1O98A 1ELZA 3SZZA 1AJDA 3T02A 1URBA 1AJAA 2ANHA 1KH4A 3CMRA 3MK2A 1KH9A 2IFYA 1E33P 2QZUA 3M7VA 2GLQA 1KH5A 3IGZB 3SZYA 1KHLA 3M8YA 3T01A 1EW9A 3UNYA 1ALKA 1KHJA 1P49A 1ZEDA 1ZEBA 1AUKA 1AJCA 1EJJA 4FDIA 1ALHA 1E1ZP
chains in the KnotProt database with same CATH topology
4FDJA 1AJBA 1HDHA 1SHQA 1HJKA 1KHNA 1K7HA 3M8WA 3BDGA 3UN2A 1E3CP 1ED8A 3OT9A 1EW8A 1ELYA 3UO0A 1EI6A 3IGYB 3MK0A 3BDHA 3UN5A 1ED9A 1N2LA 1URAA 1SHNA 3TX0A 1B8JA 1E2SP 1ALJA 1Y7AA 1ELXA 1KH7A 1ZEFA 1HQAA 1Y6VA 2G9YA 3M8ZA 3NVLA 1EQJA 2GA3A 1ALIA 1FSUA 3TWZA 1KHKA 3BDFA 1ANIA 3ED4A 3UN3A 3BDGB 3MK1A 3DPCA 1O99A 3T00A 1N2KA 1ANJA 3DYCA 1EW2A 1O98A 1ELZA 3SZZA 1AJDA 3T02A 1URBA 1AJAA 2ANHA 1KH4A 3CMRA 3MK2A 1KH9A 2IFYA 1E33P 2QZUA 3M7VA 2GLQA 1KH5A 3IGZB 3SZYA 1KHLA 3M8YA 3T01A 1EW9A 3UNYA 1ALKA 1KHJA 1P49A 1ZEDA 1ZEBA 1AUKA 1AJCA 1EJJA 4FDIA 1ALHA 1E1ZP
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 4FDJ A;  1AJB A;  1HDH A;  1SHQ A;  1HJK A;  1KHN A;  1K7H A;  3M8W A;  3BDG A;  3UN2 A;  1E3C P;  1ED8 A;  3OT9 A;  1EW8 A;  1ELY A;  3UO0 A;  1EI6 A;  3IGY B;  3MK0 A;  3BDH A;  3UN5 A;  1ED9 A;  1N2L A;  1URA A;  1SHN A;  3TX0 A;  1B8J A;  1E2S P;  1ALJ A;  1Y7A A;  1ELX A;  1KH7 A;  1ZEF A;  1HQA A;  1Y6V A;  2G9Y A;  3M8Z A;  3NVL A;  1EQJ A;  2GA3 A;  1ALI A;  1FSU A;  3TWZ A;  1KHK A;  3BDF A;  1ANI A;  3ED4 A;  3UN3 A;  3BDG B;  3MK1 A;  3DPC A;  1O99 A;  3T00 A;  1N2K A;  1ANJ A;  3DYC A;  1EW2 A;  1O98 A;  1ELZ A;  3SZZ A;  1AJD A;  3T02 A;  1URB A;  1AJA A;  2ANH A;  1KH4 A;  3CMR A;  3MK2 A;  1KH9 A;  2IFY A;  1E33 P;  2QZU A;  3M7V A;  2GLQ A;  1KH5 A;  3IGZ B;  3SZY A;  1KHL A;  3M8Y A;  3T01 A;  1EW9 A;  3UNY A;  1ALK A;  1KHJ A;  1P49 A;  1ZED A;  1ZEB A;  1AUK A;  1AJC A;  1EJJ A;  4FDI A;  1ALH A;  1E1Z P; 
#chains in the KnotProt database with same CATH topology
 4FDJ A;  1AJB A;  1HDH A;  1SHQ A;  1HJK A;  1KHN A;  1K7H A;  3M8W A;  3BDG A;  3UN2 A;  1E3C P;  1ED8 A;  3OT9 A;  1EW8 A;  1ELY A;  3UO0 A;  1EI6 A;  3IGY B;  3MK0 A;  3BDH A;  3UN5 A;  1ED9 A;  1N2L A;  1URA A;  1SHN A;  3TX0 A;  1B8J A;  1E2S P;  1ALJ A;  1Y7A A;  1ELX A;  1KH7 A;  1ZEF A;  1HQA A;  1Y6V A;  2G9Y A;  3M8Z A;  3NVL A;  1EQJ A;  2GA3 A;  1ALI A;  1FSU A;  3TWZ A;  1KHK A;  3BDF A;  1ANI A;  3ED4 A;  3UN3 A;  3BDG B;  3MK1 A;  3DPC A;  1O99 A;  3T00 A;  1N2K A;  1ANJ A;  3DYC A;  1EW2 A;  1O98 A;  1ELZ A;  3SZZ A;  1AJD A;  3T02 A;  1URB A;  1AJA A;  2ANH A;  1KH4 A;  3CMR A;  3MK2 A;  1KH9 A;  2IFY A;  1E33 P;  2QZU A;  3M7V A;  2GLQ A;  1KH5 A;  3IGZ B;  3SZY A;  1KHL A;  3M8Y A;  3T01 A;  1EW9 A;  3UNY A;  1ALK A;  1KHJ A;  1P49 A;  1ZED A;  1ZEB A;  1AUK A;  1AJC A;  1EJJ A;  4FDI A;  1ALH A;  1E1Z P; 
#chains in the KnotProt database with same CATH homology
 4FDJ A;  1AJB A;  1HDH A;  1SHQ A;  1HJK A;  1KHN A;  1K7H A;  3M8W A;  3BDG A;  3UN2 A;  1E3C P;  1ED8 A;  3OT9 A;  1EW8 A;  1ELY A;  3UO0 A;  1EI6 A;  3IGY B;  3MK0 A;  3BDH A;  3UN5 A;  1ED9 A;  1N2L A;  1URA A;  1SHN A;  3TX0 A;  1B8J A;  1E2S P;  1ALJ A;  1Y7A A;  1ELX A;  1KH7 A;  1ZEF A;  1HQA A;  1Y6V A;  2G9Y A;  3M8Z A;  3NVL A;  1EQJ A;  2GA3 A;  1ALI A;  1FSU A;  3TWZ A;  1KHK A;  3BDF A;  1ANI A;  3ED4 A;  3UN3 A;  3BDG B;  3MK1 A;  3DPC A;  1O99 A;  3T00 A;  1N2K A;  1ANJ A;  3DYC A;  1EW2 A;  1O98 A;  1ELZ A;  3SZZ A;  1AJD A;  3T02 A;  1URB A;  1AJA A;  2ANH A;  1KH4 A;  3CMR A;  3MK2 A;  1KH9 A;  2IFY A;  1E33 P;  2QZU A;  3M7V A;  2GLQ A;  1KH5 A;  3IGZ B;  3SZY A;  1KHL A;  3M8Y A;  3T01 A;  1EW9 A;  3UNY A;  1ALK A;  1KHJ A;  1P49 A;  1ZED A;  1ZEB A;  1AUK A;  1AJC A;  1EJJ A;  4FDI A;  1ALH A;  1E1Z P; 
...loading similar chains, please wait...
similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling