1O99A

Crystal structure of the s62a mutant of phosphoglycerate mutase from bacillus stearothermophilus complexed with 2-phosphoglycerate
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 7-444 438 1-6 466-509 445-465 6 44 slipknot
Chain Sequence
SKKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNAEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 5-445 441 1-4 451-509 446-450 4 59 slipknot
view details
3.1 6-450 445 1-5 460-509 451-459 5 50 slipknot
view details
2.1 4-459 456 1-3 464-509 460-463 3 46 slipknot
sequence length 509
structure length 509
publication title Insights Into the Catalytic Mechanism of Cofactor-Independent Phosphoglycerate Mutase from X-Ray Crystallography, Simulated Dynamics and Molecular Modeling
pubmed doi rcsb
molecule tags Isomerase
molecule keywords 2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE
source organism Bacillus stearothermophilus
total genus Genus: 195
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2002-12-11
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1o99A02
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain 1o99A01
3MK2A 1ZEDA 3M7VA 1N2LA 4FDJA 1ANJA 3IGYB 1ALKA 1N2KA 3ED4A 3MK0A 3M8WA 1O98A 1EW8A 1AUKA 1KH4A 1KHNA 3DYCA 1E1ZP 1ELYA 1ALHA 2IFYA 3UNYA 1KH9A 1EJJA 1EQJA 2GLQA 3T02A 1KH5A 3BDHA 1KH7A 1FSUA 1AJBA 3DPCA 1ALIA 1Y6VA 1ELZA 1ZEBA 3BDGA 3BDGB 1O99A 1SHNA 2ANHA 1ZEFA 3BDFA 3UN2A 1KHJA 1P49A 1EW2A 3MK1A 1E3CP 1AJAA 3CMRA 1EI6A 1URAA 1AJDA 1KHLA 1URBA 1K7HA 1SHQA 3M8ZA 3UN3A 3NVLA 3T00A 2QZUA 1E2SP 1KHKA 3TX0A 3IGZB 2GA3A 1E33P 2G9YA 1HJKA 3T01A 3SZZA 1ED8A 3TWZA 1B8JA 1ELXA 1ED9A 1AJCA 1ANIA 3UN5A 1HQAA 3SZYA 1Y7AA 1HDHA 3UO0A 3M8YA 1EW9A 3OT9A 4FDIA 1ALJA
chains in the KnotProt database with same CATH superfamily
3MK2A 1ZEDA 3M7VA 1N2LA 4FDJA 1ANJA 3IGYB 1ALKA 1N2KA 3ED4A 3MK0A 3M8WA 1O98A 1EW8A 1AUKA 1KH4A 1KHNA 3DYCA 1E1ZP 1ELYA 1ALHA 2IFYA 3UNYA 1KH9A 1EJJA 1EQJA 2GLQA 3T02A 1KH5A 3BDHA 1KH7A 1FSUA 1AJBA 3DPCA 1ALIA 1Y6VA 1ELZA 1ZEBA 3BDGA 3BDGB 1O99A 1SHNA 2ANHA 1ZEFA 3BDFA 3UN2A 1KHJA 1P49A 1EW2A 3MK1A 1E3CP 1AJAA 3CMRA 1EI6A 1URAA 1AJDA 1KHLA 1URBA 1K7HA 1SHQA 3M8ZA 3UN3A 3NVLA 3T00A 2QZUA 1E2SP 1KHKA 3TX0A 3IGZB 2GA3A 1E33P 2G9YA 1HJKA 3T01A 3SZZA 1ED8A 3TWZA 1B8JA 1ELXA 1ED9A 1AJCA 1ANIA 3UN5A 1HQAA 3SZYA 1Y7AA 1HDHA 3UO0A 3M8YA 1EW9A 3OT9A 4FDIA 1ALJA
chains in the KnotProt database with same CATH topology
3MK2A 1ZEDA 3M7VA 1N2LA 4FDJA 1ANJA 3IGYB 1ALKA 1N2KA 3ED4A 3MK0A 3M8WA 1O98A 1EW8A 1AUKA 1KH4A 1KHNA 3DYCA 1E1ZP 1ELYA 1ALHA 2IFYA 3UNYA 1KH9A 1EJJA 1EQJA 2GLQA 3T02A 1KH5A 3BDHA 1KH7A 1FSUA 1AJBA 3DPCA 1ALIA 1Y6VA 1ELZA 1ZEBA 3BDGA 3BDGB 1O99A 1SHNA 2ANHA 1ZEFA 3BDFA 3UN2A 1KHJA 1P49A 1EW2A 3MK1A 1E3CP 1AJAA 3CMRA 1EI6A 1URAA 1AJDA 1KHLA 1URBA 1K7HA 1SHQA 3M8ZA 3UN3A 3NVLA 3T00A 2QZUA 1E2SP 1KHKA 3TX0A 3IGZB 2GA3A 1E33P 2G9YA 1HJKA 3T01A 3SZZA 1ED8A 3TWZA 1B8JA 1ELXA 1ED9A 1AJCA 1ANIA 3UN5A 1HQAA 3SZYA 1Y7AA 1HDHA 3UO0A 3M8YA 1EW9A 3OT9A 4FDIA 1ALJA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 3MK2 A;  1ZED A;  3M7V A;  1N2L A;  4FDJ A;  1ANJ A;  3IGY B;  1ALK A;  1N2K A;  3ED4 A;  3MK0 A;  3M8W A;  1O98 A;  1EW8 A;  1AUK A;  1KH4 A;  1KHN A;  3DYC A;  1E1Z P;  1ELY A;  1ALH A;  2IFY A;  3UNY A;  1KH9 A;  1EJJ A;  1EQJ A;  2GLQ A;  3T02 A;  1KH5 A;  3BDH A;  1KH7 A;  1FSU A;  1AJB A;  3DPC A;  1ALI A;  1Y6V A;  1ELZ A;  1ZEB A;  3BDG A;  3BDG B;  1O99 A;  1SHN A;  2ANH A;  1ZEF A;  3BDF A;  3UN2 A;  1KHJ A;  1P49 A;  1EW2 A;  3MK1 A;  1E3C P;  1AJA A;  3CMR A;  1EI6 A;  1URA A;  1AJD A;  1KHL A;  1URB A;  1K7H A;  1SHQ A;  3M8Z A;  3UN3 A;  3NVL A;  3T00 A;  2QZU A;  1E2S P;  1KHK A;  3TX0 A;  3IGZ B;  2GA3 A;  1E33 P;  2G9Y A;  1HJK A;  3T01 A;  3SZZ A;  1ED8 A;  3TWZ A;  1B8J A;  1ELX A;  1ED9 A;  1AJC A;  1ANI A;  3UN5 A;  1HQA A;  3SZY A;  1Y7A A;  1HDH A;  3UO0 A;  3M8Y A;  1EW9 A;  3OT9 A;  4FDI A;  1ALJ A; 
#chains in the KnotProt database with same CATH topology
 3MK2 A;  1ZED A;  3M7V A;  1N2L A;  4FDJ A;  1ANJ A;  3IGY B;  1ALK A;  1N2K A;  3ED4 A;  3MK0 A;  3M8W A;  1O98 A;  1EW8 A;  1AUK A;  1KH4 A;  1KHN A;  3DYC A;  1E1Z P;  1ELY A;  1ALH A;  2IFY A;  3UNY A;  1KH9 A;  1EJJ A;  1EQJ A;  2GLQ A;  3T02 A;  1KH5 A;  3BDH A;  1KH7 A;  1FSU A;  1AJB A;  3DPC A;  1ALI A;  1Y6V A;  1ELZ A;  1ZEB A;  3BDG A;  3BDG B;  1O99 A;  1SHN A;  2ANH A;  1ZEF A;  3BDF A;  3UN2 A;  1KHJ A;  1P49 A;  1EW2 A;  3MK1 A;  1E3C P;  1AJA A;  3CMR A;  1EI6 A;  1URA A;  1AJD A;  1KHL A;  1URB A;  1K7H A;  1SHQ A;  3M8Z A;  3UN3 A;  3NVL A;  3T00 A;  2QZU A;  1E2S P;  1KHK A;  3TX0 A;  3IGZ B;  2GA3 A;  1E33 P;  2G9Y A;  1HJK A;  3T01 A;  3SZZ A;  1ED8 A;  3TWZ A;  1B8J A;  1ELX A;  1ED9 A;  1AJC A;  1ANI A;  3UN5 A;  1HQA A;  3SZY A;  1Y7A A;  1HDH A;  3UO0 A;  3M8Y A;  1EW9 A;  3OT9 A;  4FDI A;  1ALJ A; 
#chains in the KnotProt database with same CATH homology
 3MK2 A;  1ZED A;  3M7V A;  1N2L A;  4FDJ A;  1ANJ A;  3IGY B;  1ALK A;  1N2K A;  3ED4 A;  3MK0 A;  3M8W A;  1O98 A;  1EW8 A;  1AUK A;  1KH4 A;  1KHN A;  3DYC A;  1E1Z P;  1ELY A;  1ALH A;  2IFY A;  3UNY A;  1KH9 A;  1EJJ A;  1EQJ A;  2GLQ A;  3T02 A;  1KH5 A;  3BDH A;  1KH7 A;  1FSU A;  1AJB A;  3DPC A;  1ALI A;  1Y6V A;  1ELZ A;  1ZEB A;  3BDG A;  3BDG B;  1O99 A;  1SHN A;  2ANH A;  1ZEF A;  3BDF A;  3UN2 A;  1KHJ A;  1P49 A;  1EW2 A;  3MK1 A;  1E3C P;  1AJA A;  3CMR A;  1EI6 A;  1URA A;  1AJD A;  1KHL A;  1URB A;  1K7H A;  1SHQ A;  3M8Z A;  3UN3 A;  3NVL A;  3T00 A;  2QZU A;  1E2S P;  1KHK A;  3TX0 A;  3IGZ B;  2GA3 A;  1E33 P;  2G9Y A;  1HJK A;  3T01 A;  3SZZ A;  1ED8 A;  3TWZ A;  1B8J A;  1ELX A;  1ED9 A;  1AJC A;  1ANI A;  3UN5 A;  1HQA A;  3SZY A;  1Y7A A;  1HDH A;  3UO0 A;  3M8Y A;  1EW9 A;  3OT9 A;  4FDI A;  1ALJ A; 
...loading similar chains, please wait...
similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling