1ZEDA

Alkaline phosphatase from human placenta in complex with p-nitrophenyl-phosphonate
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 40-355 316 1-39 439-481 356-438 39 43 slipknot
Chain Sequence
IIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKRQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALRLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPPAG
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 39-357 319 1-38 432-481 358-431 38 50 slipknot
view details
3.1 39-431 393 1-38 437-481 432-436 38 45 slipknot
view details
3.1 34-436 403 1-33 440-481 437-439 33 42 slipknot
view details
2.1 34-439 406 1-33 441-481 440-440 33 41 slipknot
view details
2.1 35-354 320 1-5, 358-481 6-34, 355-357 5 124 slipknot
sequence length 481
structure length 481
publication title Structural Studies of Human Placental Alkaline Phosphatase in Complex with Functional Ligands.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Alkaline phosphatase
total genus Genus: 177
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2005-04-18
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1zedA00
1Y6VA 3BDGA 1ANJA 3IGZB 1ZEFA 1AJAA 3MK0A 1FSUA 1EQJA 1ZEDA 1N2KA 1EI6A 3NVLA 3TWZA 1ALJA 3TX0A 1ELZA 3BDHA 1KH4A 3MK1A 1SHNA 1KHKA 1O98A 1ALIA 3DYCA 3ED4A 4FDJA 1E3CP 3T01A 1ED9A 1AJDA 1KH5A 3BDFA 1N2LA 1K7HA 2ANHA 3M7VA 3IGYB 3OT9A 3SZZA 3BDGB 2IFYA 1HJKA 3UO0A 1KHJA 2GLQA 3DPCA 1KHNA 1EW2A 3M8WA 1ED8A 2GA3A 1KHLA 1AJCA 1B8JA 1EW9A 3T02A 1EW8A 1KH7A 1E1ZP 1O99A 1ALKA 2QZUA 1URAA 1Y7AA 3UN2A 1KH9A 1P49A 1URBA 1ZEBA 3M8YA 3UN3A 2G9YA 1E2SP 1HDHA 3T00A 1ELYA 3MK2A 1ELXA 1AUKA 3M8ZA 1AJBA 3UNYA 1HQAA 3CMRA 1EJJA 1ANIA 1SHQA 3SZYA 1E33P 4FDIA 3UN5A
chains in the KnotProt database with same CATH superfamily
1Y6VA 3BDGA 1ANJA 3IGZB 1ZEFA 1AJAA 3MK0A 1FSUA 1EQJA 1ZEDA 1N2KA 1EI6A 3NVLA 3TWZA 1ALJA 3TX0A 1ELZA 3BDHA 1KH4A 3MK1A 1SHNA 1KHKA 1O98A 1ALIA 3DYCA 3ED4A 4FDJA 1E3CP 3T01A 1ED9A 1AJDA 1KH5A 3BDFA 1N2LA 1K7HA 2ANHA 3M7VA 3IGYB 3OT9A 3SZZA 3BDGB 2IFYA 1HJKA 3UO0A 1KHJA 2GLQA 3DPCA 1KHNA 1EW2A 3M8WA 1ED8A 2GA3A 1KHLA 1AJCA 1B8JA 1EW9A 3T02A 1EW8A 1KH7A 1E1ZP 1O99A 1ALKA 2QZUA 1URAA 1Y7AA 3UN2A 1KH9A 1P49A 1URBA 1ZEBA 3M8YA 3UN3A 2G9YA 1E2SP 1HDHA 3T00A 1ELYA 3MK2A 1ELXA 1AUKA 3M8ZA 1AJBA 3UNYA 1HQAA 3CMRA 1EJJA 1ANIA 1SHQA 3SZYA 1E33P 4FDIA 3UN5A
chains in the KnotProt database with same CATH topology
1Y6VA 3BDGA 1ANJA 3IGZB 1ZEFA 1AJAA 3MK0A 1FSUA 1EQJA 1ZEDA 1N2KA 1EI6A 3NVLA 3TWZA 1ALJA 3TX0A 1ELZA 3BDHA 1KH4A 3MK1A 1SHNA 1KHKA 1O98A 1ALIA 3DYCA 3ED4A 4FDJA 1E3CP 3T01A 1ED9A 1AJDA 1KH5A 3BDFA 1N2LA 1K7HA 2ANHA 3M7VA 3IGYB 3OT9A 3SZZA 3BDGB 2IFYA 1HJKA 3UO0A 1KHJA 2GLQA 3DPCA 1KHNA 1EW2A 3M8WA 1ED8A 2GA3A 1KHLA 1AJCA 1B8JA 1EW9A 3T02A 1EW8A 1KH7A 1E1ZP 1O99A 1ALKA 2QZUA 1URAA 1Y7AA 3UN2A 1KH9A 1P49A 1URBA 1ZEBA 3M8YA 3UN3A 2G9YA 1E2SP 1HDHA 3T00A 1ELYA 3MK2A 1ELXA 1AUKA 3M8ZA 1AJBA 3UNYA 1HQAA 3CMRA 1EJJA 1ANIA 1SHQA 3SZYA 1E33P 4FDIA 3UN5A
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1Y6V A;  3BDG A;  1ANJ A;  3IGZ B;  1ZEF A;  1AJA A;  3MK0 A;  1FSU A;  1EQJ A;  1ZED A;  1N2K A;  1EI6 A;  3NVL A;  3TWZ A;  1ALJ A;  3TX0 A;  1ELZ A;  3BDH A;  1KH4 A;  3MK1 A;  1SHN A;  1KHK A;  1O98 A;  1ALI A;  3DYC A;  3ED4 A;  4FDJ A;  1E3C P;  3T01 A;  1ED9 A;  1AJD A;  1KH5 A;  3BDF A;  1N2L A;  1K7H A;  2ANH A;  3M7V A;  3IGY B;  3OT9 A;  3SZZ A;  3BDG B;  2IFY A;  1HJK A;  3UO0 A;  1KHJ A;  2GLQ A;  3DPC A;  1KHN A;  1EW2 A;  3M8W A;  1ED8 A;  2GA3 A;  1KHL A;  1AJC A;  1B8J A;  1EW9 A;  3T02 A;  1EW8 A;  1KH7 A;  1E1Z P;  1O99 A;  1ALK A;  2QZU A;  1URA A;  1Y7A A;  3UN2 A;  1KH9 A;  1P49 A;  1URB A;  1ZEB A;  3M8Y A;  3UN3 A;  2G9Y A;  1E2S P;  1HDH A;  3T00 A;  1ELY A;  3MK2 A;  1ELX A;  1AUK A;  3M8Z A;  1AJB A;  3UNY A;  1HQA A;  3CMR A;  1EJJ A;  1ANI A;  1SHQ A;  3SZY A;  1E33 P;  4FDI A;  3UN5 A; 
#chains in the KnotProt database with same CATH topology
 1Y6V A;  3BDG A;  1ANJ A;  3IGZ B;  1ZEF A;  1AJA A;  3MK0 A;  1FSU A;  1EQJ A;  1ZED A;  1N2K A;  1EI6 A;  3NVL A;  3TWZ A;  1ALJ A;  3TX0 A;  1ELZ A;  3BDH A;  1KH4 A;  3MK1 A;  1SHN A;  1KHK A;  1O98 A;  1ALI A;  3DYC A;  3ED4 A;  4FDJ A;  1E3C P;  3T01 A;  1ED9 A;  1AJD A;  1KH5 A;  3BDF A;  1N2L A;  1K7H A;  2ANH A;  3M7V A;  3IGY B;  3OT9 A;  3SZZ A;  3BDG B;  2IFY A;  1HJK A;  3UO0 A;  1KHJ A;  2GLQ A;  3DPC A;  1KHN A;  1EW2 A;  3M8W A;  1ED8 A;  2GA3 A;  1KHL A;  1AJC A;  1B8J A;  1EW9 A;  3T02 A;  1EW8 A;  1KH7 A;  1E1Z P;  1O99 A;  1ALK A;  2QZU A;  1URA A;  1Y7A A;  3UN2 A;  1KH9 A;  1P49 A;  1URB A;  1ZEB A;  3M8Y A;  3UN3 A;  2G9Y A;  1E2S P;  1HDH A;  3T00 A;  1ELY A;  3MK2 A;  1ELX A;  1AUK A;  3M8Z A;  1AJB A;  3UNY A;  1HQA A;  3CMR A;  1EJJ A;  1ANI A;  1SHQ A;  3SZY A;  1E33 P;  4FDI A;  3UN5 A; 
#chains in the KnotProt database with same CATH homology
 1Y6V A;  3BDG A;  1ANJ A;  3IGZ B;  1ZEF A;  1AJA A;  3MK0 A;  1FSU A;  1EQJ A;  1ZED A;  1N2K A;  1EI6 A;  3NVL A;  3TWZ A;  1ALJ A;  3TX0 A;  1ELZ A;  3BDH A;  1KH4 A;  3MK1 A;  1SHN A;  1KHK A;  1O98 A;  1ALI A;  3DYC A;  3ED4 A;  4FDJ A;  1E3C P;  3T01 A;  1ED9 A;  1AJD A;  1KH5 A;  3BDF A;  1N2L A;  1K7H A;  2ANH A;  3M7V A;  3IGY B;  3OT9 A;  3SZZ A;  3BDG B;  2IFY A;  1HJK A;  3UO0 A;  1KHJ A;  2GLQ A;  3DPC A;  1KHN A;  1EW2 A;  3M8W A;  1ED8 A;  2GA3 A;  1KHL A;  1AJC A;  1B8J A;  1EW9 A;  3T02 A;  1EW8 A;  1KH7 A;  1E1Z P;  1O99 A;  1ALK A;  2QZU A;  1URA A;  1Y7A A;  3UN2 A;  1KH9 A;  1P49 A;  1URB A;  1ZEB A;  3M8Y A;  3UN3 A;  2G9Y A;  1E2S P;  1HDH A;  3T00 A;  1ELY A;  3MK2 A;  1ELX A;  1AUK A;  3M8Z A;  1AJB A;  3UNY A;  1HQA A;  3CMR A;  1EJJ A;  1ANI A;  1SHQ A;  3SZY A;  1E33 P;  4FDI A;  3UN5 A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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