2ANHA

Alkaline phosphatase (d153h)
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 43-366 324 1-42 417-446 367-416 42 30 slipknot
Chain Sequence
MPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQHATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 19-363 345 1-18 369-446 364-368 18 78 slipknot
view details
3.1 44-370 327 1-43 408-446 371-407 43 39 slipknot
view details
3.1 42-410 369 1-41 417-446 411-416 41 30 slipknot
view details
2.1 41-363 323 1-19, 370-446 20-40, 364-369 19 77 slipknot
sequence length 446
structure length 446
publication title Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases.
pubmed doi rcsb
molecule tags Alkaline phosphatase
molecule keywords ALKALINE PHOSPHATASE
source organism Escherichia coli
total genus Genus: 164
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 1995-09-06
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2anhA00
1KHNA 3ED4A 3M8YA 3IGYB 3OT9A 3M8ZA 1O98A 2QZUA 3T01A 3M8WA 3BDGA 1EW9A 1ZEBA 1KHJA 1ZEFA 1EI6A 2G9YA 1AJAA 3SZYA 1Y6VA 3UO0A 1K7HA 1HJKA 1EW8A 1KH5A 1AJDA 1P49A 1ELYA 1ELXA 3MK1A 1B8JA 2ANHA 3BDGB 4FDJA 3UN2A 1ED9A 1ALIA 1Y7AA 3MK0A 1ED8A 3SZZA 1HQAA 1KH4A 1AJCA 1EW2A 1ZEDA 2IFYA 1EJJA 1ELZA 3MK2A 3NVLA 1ALKA 3DYCA 1AJBA 1N2LA 1E1ZP 3BDFA 3T02A 1ANJA 3T00A 1FSUA 3TWZA 3UN5A 3UNYA 2GA3A 1E3CP 1SHNA 1EQJA 1KH7A 3BDHA 3DPCA 1KH9A 1ANIA 3TX0A 1KHKA 1KHLA 1O99A 1SHQA 1AUKA 1URBA 1E2SP 3CMRA 1ALJA 1URAA 3IGZB 1HDHA 1N2KA 3M7VA 1E33P 2GLQA 3UN3A 4FDIA
chains in the KnotProt database with same CATH superfamily
1KHNA 3ED4A 3M8YA 3IGYB 3OT9A 3M8ZA 1O98A 2QZUA 3T01A 3M8WA 3BDGA 1EW9A 1ZEBA 1KHJA 1ZEFA 1EI6A 2G9YA 1AJAA 3SZYA 1Y6VA 3UO0A 1K7HA 1HJKA 1EW8A 1KH5A 1AJDA 1P49A 1ELYA 1ELXA 3MK1A 1B8JA 2ANHA 3BDGB 4FDJA 3UN2A 1ED9A 1ALIA 1Y7AA 3MK0A 1ED8A 3SZZA 1HQAA 1KH4A 1AJCA 1EW2A 1ZEDA 2IFYA 1EJJA 1ELZA 3MK2A 3NVLA 1ALKA 3DYCA 1AJBA 1N2LA 1E1ZP 3BDFA 3T02A 1ANJA 3T00A 1FSUA 3TWZA 3UN5A 3UNYA 2GA3A 1E3CP 1SHNA 1EQJA 1KH7A 3BDHA 3DPCA 1KH9A 1ANIA 3TX0A 1KHKA 1KHLA 1O99A 1SHQA 1AUKA 1URBA 1E2SP 3CMRA 1ALJA 1URAA 3IGZB 1HDHA 1N2KA 3M7VA 1E33P 2GLQA 3UN3A 4FDIA
chains in the KnotProt database with same CATH topology
1KHNA 3ED4A 3M8YA 3IGYB 3OT9A 3M8ZA 1O98A 2QZUA 3T01A 3M8WA 3BDGA 1EW9A 1ZEBA 1KHJA 1ZEFA 1EI6A 2G9YA 1AJAA 3SZYA 1Y6VA 3UO0A 1K7HA 1HJKA 1EW8A 1KH5A 1AJDA 1P49A 1ELYA 1ELXA 3MK1A 1B8JA 2ANHA 3BDGB 4FDJA 3UN2A 1ED9A 1ALIA 1Y7AA 3MK0A 1ED8A 3SZZA 1HQAA 1KH4A 1AJCA 1EW2A 1ZEDA 2IFYA 1EJJA 1ELZA 3MK2A 3NVLA 1ALKA 3DYCA 1AJBA 1N2LA 1E1ZP 3BDFA 3T02A 1ANJA 3T00A 1FSUA 3TWZA 3UN5A 3UNYA 2GA3A 1E3CP 1SHNA 1EQJA 1KH7A 3BDHA 3DPCA 1KH9A 1ANIA 3TX0A 1KHKA 1KHLA 1O99A 1SHQA 1AUKA 1URBA 1E2SP 3CMRA 1ALJA 1URAA 3IGZB 1HDHA 1N2KA 3M7VA 1E33P 2GLQA 3UN3A 4FDIA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1KHN A;  3ED4 A;  3M8Y A;  3IGY B;  3OT9 A;  3M8Z A;  1O98 A;  2QZU A;  3T01 A;  3M8W A;  3BDG A;  1EW9 A;  1ZEB A;  1KHJ A;  1ZEF A;  1EI6 A;  2G9Y A;  1AJA A;  3SZY A;  1Y6V A;  3UO0 A;  1K7H A;  1HJK A;  1EW8 A;  1KH5 A;  1AJD A;  1P49 A;  1ELY A;  1ELX A;  3MK1 A;  1B8J A;  2ANH A;  3BDG B;  4FDJ A;  3UN2 A;  1ED9 A;  1ALI A;  1Y7A A;  3MK0 A;  1ED8 A;  3SZZ A;  1HQA A;  1KH4 A;  1AJC A;  1EW2 A;  1ZED A;  2IFY A;  1EJJ A;  1ELZ A;  3MK2 A;  3NVL A;  1ALK A;  3DYC A;  1AJB A;  1N2L A;  1E1Z P;  3BDF A;  3T02 A;  1ANJ A;  3T00 A;  1FSU A;  3TWZ A;  3UN5 A;  3UNY A;  2GA3 A;  1E3C P;  1SHN A;  1EQJ A;  1KH7 A;  3BDH A;  3DPC A;  1KH9 A;  1ANI A;  3TX0 A;  1KHK A;  1KHL A;  1O99 A;  1SHQ A;  1AUK A;  1URB A;  1E2S P;  3CMR A;  1ALJ A;  1URA A;  3IGZ B;  1HDH A;  1N2K A;  3M7V A;  1E33 P;  2GLQ A;  3UN3 A;  4FDI A; 
#chains in the KnotProt database with same CATH topology
 1KHN A;  3ED4 A;  3M8Y A;  3IGY B;  3OT9 A;  3M8Z A;  1O98 A;  2QZU A;  3T01 A;  3M8W A;  3BDG A;  1EW9 A;  1ZEB A;  1KHJ A;  1ZEF A;  1EI6 A;  2G9Y A;  1AJA A;  3SZY A;  1Y6V A;  3UO0 A;  1K7H A;  1HJK A;  1EW8 A;  1KH5 A;  1AJD A;  1P49 A;  1ELY A;  1ELX A;  3MK1 A;  1B8J A;  2ANH A;  3BDG B;  4FDJ A;  3UN2 A;  1ED9 A;  1ALI A;  1Y7A A;  3MK0 A;  1ED8 A;  3SZZ A;  1HQA A;  1KH4 A;  1AJC A;  1EW2 A;  1ZED A;  2IFY A;  1EJJ A;  1ELZ A;  3MK2 A;  3NVL A;  1ALK A;  3DYC A;  1AJB A;  1N2L A;  1E1Z P;  3BDF A;  3T02 A;  1ANJ A;  3T00 A;  1FSU A;  3TWZ A;  3UN5 A;  3UNY A;  2GA3 A;  1E3C P;  1SHN A;  1EQJ A;  1KH7 A;  3BDH A;  3DPC A;  1KH9 A;  1ANI A;  3TX0 A;  1KHK A;  1KHL A;  1O99 A;  1SHQ A;  1AUK A;  1URB A;  1E2S P;  3CMR A;  1ALJ A;  1URA A;  3IGZ B;  1HDH A;  1N2K A;  3M7V A;  1E33 P;  2GLQ A;  3UN3 A;  4FDI A; 
#chains in the KnotProt database with same CATH homology
 1KHN A;  3ED4 A;  3M8Y A;  3IGY B;  3OT9 A;  3M8Z A;  1O98 A;  2QZU A;  3T01 A;  3M8W A;  3BDG A;  1EW9 A;  1ZEB A;  1KHJ A;  1ZEF A;  1EI6 A;  2G9Y A;  1AJA A;  3SZY A;  1Y6V A;  3UO0 A;  1K7H A;  1HJK A;  1EW8 A;  1KH5 A;  1AJD A;  1P49 A;  1ELY A;  1ELX A;  3MK1 A;  1B8J A;  2ANH A;  3BDG B;  4FDJ A;  3UN2 A;  1ED9 A;  1ALI A;  1Y7A A;  3MK0 A;  1ED8 A;  3SZZ A;  1HQA A;  1KH4 A;  1AJC A;  1EW2 A;  1ZED A;  2IFY A;  1EJJ A;  1ELZ A;  3MK2 A;  3NVL A;  1ALK A;  3DYC A;  1AJB A;  1N2L A;  1E1Z P;  3BDF A;  3T02 A;  1ANJ A;  3T00 A;  1FSU A;  3TWZ A;  3UN5 A;  3UNY A;  2GA3 A;  1E3C P;  1SHN A;  1EQJ A;  1KH7 A;  3BDH A;  3DPC A;  1KH9 A;  1ANI A;  3TX0 A;  1KHK A;  1KHL A;  1O99 A;  1SHQ A;  1AUK A;  1URB A;  1E2S P;  3CMR A;  1ALJ A;  1URA A;  3IGZ B;  1HDH A;  1N2K A;  3M7V A;  1E33 P;  2GLQ A;  3UN3 A;  4FDI A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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