2G9YA

Structure of s102t e. coli alkaline phosphatase in presence of phosphate at 2.00 a resolution
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 47-369 323 1-46 419-449 370-418 46 31 slipknot
Chain Sequence
TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDTAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 48-370 323 1-47 416-449 371-415 47 34 slipknot
view details
3.1 46-415 370 1-45 418-449 416-417 45 32 slipknot
view details
2.1 46-417 372 1-45 421-449 418-420 45 29 slipknot
view details
3.1 20-367 348 1-12, 371-449 13-19, 368-370 12 79 slipknot
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2.1 35-367 333 1-19, 371-449 20-34, 368-370 19 79 slipknot
view details
2.1 37-367 331 1-34, 371-449 35-36, 368-370 34 79 slipknot
sequence length 449
structure length 449
publication title Trapping the tetrahedral intermediate in the alkaline phosphatase reaction by substitution of the active site serine with threonine.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Alkaline phosphatase
source organism Escherichia coli
total genus Genus: 161
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2006-03-07
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2g9yA00
1KHLA 3BDGA 3MK1A 1ED9A 1ELXA 1P49A 3TX0A 3T00A 1ANJA 3NVLA 1EI6A 1AJBA 3UNYA 1EJJA 3MK0A 1URAA 3UN3A 4FDJA 3UN2A 1AJDA 1ZEFA 1B8JA 1SHQA 3IGZB 3BDHA 2GA3A 3MK2A 1URBA 1KH5A 1ANIA 1HQAA 1SHNA 3CMRA 1N2LA 1KHKA 3BDGB 1E1ZP 1O99A 3T01A 3M8YA 3UN5A 2GLQA 1KH7A 1K7HA 1ELZA 4FDIA 1EQJA 1ELYA 3DYCA 1EW8A 3ED4A 1KHJA 3TWZA 1N2KA 3SZYA 1E3CP 1ZEBA 1EW9A 1HJKA 3M7VA 2IFYA 3M8WA 1ALJA 1AUKA 1Y6VA 1E2SP 3BDFA 3IGYB 1AJAA 1O98A 3T02A 1ED8A 2G9YA 1HDHA 1ALKA 3UO0A 2ANHA 1EW2A 1Y7AA 1FSUA 1ZEDA 1ALIA 3OT9A 2QZUA 1AJCA 1KH4A 3SZZA 1E33P 3DPCA 1KHNA 1KH9A 3M8ZA
chains in the KnotProt database with same CATH superfamily
1KHLA 3BDGA 3MK1A 1ED9A 1ELXA 1P49A 3TX0A 3T00A 1ANJA 3NVLA 1EI6A 1AJBA 3UNYA 1EJJA 3MK0A 1URAA 3UN3A 4FDJA 3UN2A 1AJDA 1ZEFA 1B8JA 1SHQA 3IGZB 3BDHA 2GA3A 3MK2A 1URBA 1KH5A 1ANIA 1HQAA 1SHNA 3CMRA 1N2LA 1KHKA 3BDGB 1E1ZP 1O99A 3T01A 3M8YA 3UN5A 2GLQA 1KH7A 1K7HA 1ELZA 4FDIA 1EQJA 1ELYA 3DYCA 1EW8A 3ED4A 1KHJA 3TWZA 1N2KA 3SZYA 1E3CP 1ZEBA 1EW9A 1HJKA 3M7VA 2IFYA 3M8WA 1ALJA 1AUKA 1Y6VA 1E2SP 3BDFA 3IGYB 1AJAA 1O98A 3T02A 1ED8A 2G9YA 1HDHA 1ALKA 3UO0A 2ANHA 1EW2A 1Y7AA 1FSUA 1ZEDA 1ALIA 3OT9A 2QZUA 1AJCA 1KH4A 3SZZA 1E33P 3DPCA 1KHNA 1KH9A 3M8ZA
chains in the KnotProt database with same CATH topology
1KHLA 3BDGA 3MK1A 1ED9A 1ELXA 1P49A 3TX0A 3T00A 1ANJA 3NVLA 1EI6A 1AJBA 3UNYA 1EJJA 3MK0A 1URAA 3UN3A 4FDJA 3UN2A 1AJDA 1ZEFA 1B8JA 1SHQA 3IGZB 3BDHA 2GA3A 3MK2A 1URBA 1KH5A 1ANIA 1HQAA 1SHNA 3CMRA 1N2LA 1KHKA 3BDGB 1E1ZP 1O99A 3T01A 3M8YA 3UN5A 2GLQA 1KH7A 1K7HA 1ELZA 4FDIA 1EQJA 1ELYA 3DYCA 1EW8A 3ED4A 1KHJA 3TWZA 1N2KA 3SZYA 1E3CP 1ZEBA 1EW9A 1HJKA 3M7VA 2IFYA 3M8WA 1ALJA 1AUKA 1Y6VA 1E2SP 3BDFA 3IGYB 1AJAA 1O98A 3T02A 1ED8A 2G9YA 1HDHA 1ALKA 3UO0A 2ANHA 1EW2A 1Y7AA 1FSUA 1ZEDA 1ALIA 3OT9A 2QZUA 1AJCA 1KH4A 3SZZA 1E33P 3DPCA 1KHNA 1KH9A 3M8ZA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 1KHL A;  3BDG A;  3MK1 A;  1ED9 A;  1ELX A;  1P49 A;  3TX0 A;  3T00 A;  1ANJ A;  3NVL A;  1EI6 A;  1AJB A;  3UNY A;  1EJJ A;  3MK0 A;  1URA A;  3UN3 A;  4FDJ A;  3UN2 A;  1AJD A;  1ZEF A;  1B8J A;  1SHQ A;  3IGZ B;  3BDH A;  2GA3 A;  3MK2 A;  1URB A;  1KH5 A;  1ANI A;  1HQA A;  1SHN A;  3CMR A;  1N2L A;  1KHK A;  3BDG B;  1E1Z P;  1O99 A;  3T01 A;  3M8Y A;  3UN5 A;  2GLQ A;  1KH7 A;  1K7H A;  1ELZ A;  4FDI A;  1EQJ A;  1ELY A;  3DYC A;  1EW8 A;  3ED4 A;  1KHJ A;  3TWZ A;  1N2K A;  3SZY A;  1E3C P;  1ZEB A;  1EW9 A;  1HJK A;  3M7V A;  2IFY A;  3M8W A;  1ALJ A;  1AUK A;  1Y6V A;  1E2S P;  3BDF A;  3IGY B;  1AJA A;  1O98 A;  3T02 A;  1ED8 A;  2G9Y A;  1HDH A;  1ALK A;  3UO0 A;  2ANH A;  1EW2 A;  1Y7A A;  1FSU A;  1ZED A;  1ALI A;  3OT9 A;  2QZU A;  1AJC A;  1KH4 A;  3SZZ A;  1E33 P;  3DPC A;  1KHN A;  1KH9 A;  3M8Z A; 
#chains in the KnotProt database with same CATH topology
 1KHL A;  3BDG A;  3MK1 A;  1ED9 A;  1ELX A;  1P49 A;  3TX0 A;  3T00 A;  1ANJ A;  3NVL A;  1EI6 A;  1AJB A;  3UNY A;  1EJJ A;  3MK0 A;  1URA A;  3UN3 A;  4FDJ A;  3UN2 A;  1AJD A;  1ZEF A;  1B8J A;  1SHQ A;  3IGZ B;  3BDH A;  2GA3 A;  3MK2 A;  1URB A;  1KH5 A;  1ANI A;  1HQA A;  1SHN A;  3CMR A;  1N2L A;  1KHK A;  3BDG B;  1E1Z P;  1O99 A;  3T01 A;  3M8Y A;  3UN5 A;  2GLQ A;  1KH7 A;  1K7H A;  1ELZ A;  4FDI A;  1EQJ A;  1ELY A;  3DYC A;  1EW8 A;  3ED4 A;  1KHJ A;  3TWZ A;  1N2K A;  3SZY A;  1E3C P;  1ZEB A;  1EW9 A;  1HJK A;  3M7V A;  2IFY A;  3M8W A;  1ALJ A;  1AUK A;  1Y6V A;  1E2S P;  3BDF A;  3IGY B;  1AJA A;  1O98 A;  3T02 A;  1ED8 A;  2G9Y A;  1HDH A;  1ALK A;  3UO0 A;  2ANH A;  1EW2 A;  1Y7A A;  1FSU A;  1ZED A;  1ALI A;  3OT9 A;  2QZU A;  1AJC A;  1KH4 A;  3SZZ A;  1E33 P;  3DPC A;  1KHN A;  1KH9 A;  3M8Z A; 
#chains in the KnotProt database with same CATH homology
 1KHL A;  3BDG A;  3MK1 A;  1ED9 A;  1ELX A;  1P49 A;  3TX0 A;  3T00 A;  1ANJ A;  3NVL A;  1EI6 A;  1AJB A;  3UNY A;  1EJJ A;  3MK0 A;  1URA A;  3UN3 A;  4FDJ A;  3UN2 A;  1AJD A;  1ZEF A;  1B8J A;  1SHQ A;  3IGZ B;  3BDH A;  2GA3 A;  3MK2 A;  1URB A;  1KH5 A;  1ANI A;  1HQA A;  1SHN A;  3CMR A;  1N2L A;  1KHK A;  3BDG B;  1E1Z P;  1O99 A;  3T01 A;  3M8Y A;  3UN5 A;  2GLQ A;  1KH7 A;  1K7H A;  1ELZ A;  4FDI A;  1EQJ A;  1ELY A;  3DYC A;  1EW8 A;  3ED4 A;  1KHJ A;  3TWZ A;  1N2K A;  3SZY A;  1E3C P;  1ZEB A;  1EW9 A;  1HJK A;  3M7V A;  2IFY A;  3M8W A;  1ALJ A;  1AUK A;  1Y6V A;  1E2S P;  3BDF A;  3IGY B;  1AJA A;  1O98 A;  3T02 A;  1ED8 A;  2G9Y A;  1HDH A;  1ALK A;  3UO0 A;  2ANH A;  1EW2 A;  1Y7A A;  1FSU A;  1ZED A;  1ALI A;  3OT9 A;  2QZU A;  1AJC A;  1KH4 A;  3SZZ A;  1E33 P;  3DPC A;  1KHN A;  1KH9 A;  3M8Z A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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