3DPCA

Structure of e.coli alkaline phosphatase mutant in complex with a phosphorylated peptide
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 147
Slipknot S +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 46-366 321 1-45 418-449 367-417 45 32 slipknot
Chain Sequence
PEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDLAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLKH
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.1 43-367 325 1-42 375-449 368-374 42 75 slipknot
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3.1 46-372 327 1-45 408-449 373-407 45 42 slipknot
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3.1 44-407 364 1-43 411-449 408-410 43 39 slipknot
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3.1 44-411 368 1-43 417-449 412-416 43 33 slipknot
sequence length 449
structure length 449
publication title Development of a universal phosphorylated peptide-binding protein for simultaneous assay of kinases
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Alkaline phosphatase
source organism Escherichia coli
total genus Genus: 147
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2008-07-07
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3dpcA00
3MK2A 1O98A 3TX0A 1N2KA 1Y7AA 1P49A 1EJJA 1ED9A 1URAA 1AJCA 1ED8A 3CMRA 3OT9A 3BDFA 1URBA 1EW8A 3TWZA 3MK0A 3M8ZA 1ALKA 1ANIA 1ELYA 1EW2A 3UO0A 1E2SP 1E3CP 3UN2A 1KH4A 3T00A 1SHQA 3MK1A 1K7HA 1SHNA 3BDHA 2QZUA 1ALJA 1AJDA 1KH9A 1AJAA 1AUKA 3M8YA 3BDGB 3UN3A 1ELXA 1EW9A 3IGYB 1KHKA 3T02A 2ANHA 1ELZA 3UNYA 4FDJA 2IFYA 3UN5A 1HDHA 3SZYA 1B8JA 1ALIA 3NVLA 1HQAA 1KH7A 1KHJA 2G9YA 1HJKA 3BDGA 1ANJA 3T01A 1E33P 1Y6VA 1KHNA 1AJBA 2GA3A 1O99A 1E1ZP 1EQJA 2GLQA 1ZEBA 3DPCA 3SZZA 3IGZB 4FDIA 1KH5A 3M8WA 1KHLA 1FSUA 3M7VA 3ED4A 1EI6A 3DYCA 1ZEDA 1N2LA 1ZEFA
chains in the KnotProt database with same CATH superfamily
3MK2A 1O98A 3TX0A 1N2KA 1Y7AA 1P49A 1EJJA 1ED9A 1URAA 1AJCA 1ED8A 3CMRA 3OT9A 3BDFA 1URBA 1EW8A 3TWZA 3MK0A 3M8ZA 1ALKA 1ANIA 1ELYA 1EW2A 3UO0A 1E2SP 1E3CP 3UN2A 1KH4A 3T00A 1SHQA 3MK1A 1K7HA 1SHNA 3BDHA 2QZUA 1ALJA 1AJDA 1KH9A 1AJAA 1AUKA 3M8YA 3BDGB 3UN3A 1ELXA 1EW9A 3IGYB 1KHKA 3T02A 2ANHA 1ELZA 3UNYA 4FDJA 2IFYA 3UN5A 1HDHA 3SZYA 1B8JA 1ALIA 3NVLA 1HQAA 1KH7A 1KHJA 2G9YA 1HJKA 3BDGA 1ANJA 3T01A 1E33P 1Y6VA 1KHNA 1AJBA 2GA3A 1O99A 1E1ZP 1EQJA 2GLQA 1ZEBA 3DPCA 3SZZA 3IGZB 4FDIA 1KH5A 3M8WA 1KHLA 1FSUA 3M7VA 3ED4A 1EI6A 3DYCA 1ZEDA 1N2LA 1ZEFA
chains in the KnotProt database with same CATH topology
3MK2A 1O98A 3TX0A 1N2KA 1Y7AA 1P49A 1EJJA 1ED9A 1URAA 1AJCA 1ED8A 3CMRA 3OT9A 3BDFA 1URBA 1EW8A 3TWZA 3MK0A 3M8ZA 1ALKA 1ANIA 1ELYA 1EW2A 3UO0A 1E2SP 1E3CP 3UN2A 1KH4A 3T00A 1SHQA 3MK1A 1K7HA 1SHNA 3BDHA 2QZUA 1ALJA 1AJDA 1KH9A 1AJAA 1AUKA 3M8YA 3BDGB 3UN3A 1ELXA 1EW9A 3IGYB 1KHKA 3T02A 2ANHA 1ELZA 3UNYA 4FDJA 2IFYA 3UN5A 1HDHA 3SZYA 1B8JA 1ALIA 3NVLA 1HQAA 1KH7A 1KHJA 2G9YA 1HJKA 3BDGA 1ANJA 3T01A 1E33P 1Y6VA 1KHNA 1AJBA 2GA3A 1O99A 1E1ZP 1EQJA 2GLQA 1ZEBA 3DPCA 3SZZA 3IGZB 4FDIA 1KH5A 3M8WA 1KHLA 1FSUA 3M7VA 3ED4A 1EI6A 3DYCA 1ZEDA 1N2LA 1ZEFA
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 3MK2 A;  1O98 A;  3TX0 A;  1N2K A;  1Y7A A;  1P49 A;  1EJJ A;  1ED9 A;  1URA A;  1AJC A;  1ED8 A;  3CMR A;  3OT9 A;  3BDF A;  1URB A;  1EW8 A;  3TWZ A;  3MK0 A;  3M8Z A;  1ALK A;  1ANI A;  1ELY A;  1EW2 A;  3UO0 A;  1E2S P;  1E3C P;  3UN2 A;  1KH4 A;  3T00 A;  1SHQ A;  3MK1 A;  1K7H A;  1SHN A;  3BDH A;  2QZU A;  1ALJ A;  1AJD A;  1KH9 A;  1AJA A;  1AUK A;  3M8Y A;  3BDG B;  3UN3 A;  1ELX A;  1EW9 A;  3IGY B;  1KHK A;  3T02 A;  2ANH A;  1ELZ A;  3UNY A;  4FDJ A;  2IFY A;  3UN5 A;  1HDH A;  3SZY A;  1B8J A;  1ALI A;  3NVL A;  1HQA A;  1KH7 A;  1KHJ A;  2G9Y A;  1HJK A;  3BDG A;  1ANJ A;  3T01 A;  1E33 P;  1Y6V A;  1KHN A;  1AJB A;  2GA3 A;  1O99 A;  1E1Z P;  1EQJ A;  2GLQ A;  1ZEB A;  3DPC A;  3SZZ A;  3IGZ B;  4FDI A;  1KH5 A;  3M8W A;  1KHL A;  1FSU A;  3M7V A;  3ED4 A;  1EI6 A;  3DYC A;  1ZED A;  1N2L A;  1ZEF A; 
#chains in the KnotProt database with same CATH topology
 3MK2 A;  1O98 A;  3TX0 A;  1N2K A;  1Y7A A;  1P49 A;  1EJJ A;  1ED9 A;  1URA A;  1AJC A;  1ED8 A;  3CMR A;  3OT9 A;  3BDF A;  1URB A;  1EW8 A;  3TWZ A;  3MK0 A;  3M8Z A;  1ALK A;  1ANI A;  1ELY A;  1EW2 A;  3UO0 A;  1E2S P;  1E3C P;  3UN2 A;  1KH4 A;  3T00 A;  1SHQ A;  3MK1 A;  1K7H A;  1SHN A;  3BDH A;  2QZU A;  1ALJ A;  1AJD A;  1KH9 A;  1AJA A;  1AUK A;  3M8Y A;  3BDG B;  3UN3 A;  1ELX A;  1EW9 A;  3IGY B;  1KHK A;  3T02 A;  2ANH A;  1ELZ A;  3UNY A;  4FDJ A;  2IFY A;  3UN5 A;  1HDH A;  3SZY A;  1B8J A;  1ALI A;  3NVL A;  1HQA A;  1KH7 A;  1KHJ A;  2G9Y A;  1HJK A;  3BDG A;  1ANJ A;  3T01 A;  1E33 P;  1Y6V A;  1KHN A;  1AJB A;  2GA3 A;  1O99 A;  1E1Z P;  1EQJ A;  2GLQ A;  1ZEB A;  3DPC A;  3SZZ A;  3IGZ B;  4FDI A;  1KH5 A;  3M8W A;  1KHL A;  1FSU A;  3M7V A;  3ED4 A;  1EI6 A;  3DYC A;  1ZED A;  1N2L A;  1ZEF A; 
#chains in the KnotProt database with same CATH homology
 3MK2 A;  1O98 A;  3TX0 A;  1N2K A;  1Y7A A;  1P49 A;  1EJJ A;  1ED9 A;  1URA A;  1AJC A;  1ED8 A;  3CMR A;  3OT9 A;  3BDF A;  1URB A;  1EW8 A;  3TWZ A;  3MK0 A;  3M8Z A;  1ALK A;  1ANI A;  1ELY A;  1EW2 A;  3UO0 A;  1E2S P;  1E3C P;  3UN2 A;  1KH4 A;  3T00 A;  1SHQ A;  3MK1 A;  1K7H A;  1SHN A;  3BDH A;  2QZU A;  1ALJ A;  1AJD A;  1KH9 A;  1AJA A;  1AUK A;  3M8Y A;  3BDG B;  3UN3 A;  1ELX A;  1EW9 A;  3IGY B;  1KHK A;  3T02 A;  2ANH A;  1ELZ A;  3UNY A;  4FDJ A;  2IFY A;  3UN5 A;  1HDH A;  3SZY A;  1B8J A;  1ALI A;  3NVL A;  1HQA A;  1KH7 A;  1KHJ A;  2G9Y A;  1HJK A;  3BDG A;  1ANJ A;  3T01 A;  1E33 P;  1Y6V A;  1KHN A;  1AJB A;  2GA3 A;  1O99 A;  1E1Z P;  1EQJ A;  2GLQ A;  1ZEB A;  3DPC A;  3SZZ A;  3IGZ B;  4FDI A;  1KH5 A;  3M8W A;  1KHL A;  1FSU A;  3M7V A;  3ED4 A;  1EI6 A;  3DYC A;  1ZED A;  1N2L A;  1ZEF A;
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling