3DPCA

Structure of e.coli alkaline phosphatase mutant in complex with a phosphorylated peptide
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 46-366 321 1-45 418-449 367-417 45 32 slipknot
Chain Sequence
PEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDLAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLKH
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 43-367 325 1-42 375-449 368-374 42 75 slipknot
view details
3.1 46-372 327 1-45 408-449 373-407 45 42 slipknot
view details
3.1 44-407 364 1-43 411-449 408-410 43 39 slipknot
view details
3.1 44-411 368 1-43 417-449 412-416 43 33 slipknot
sequence length 449
structure length 449
publication title Development of a universal phosphorylated peptide-binding protein for simultaneous assay of kinases
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Alkaline phosphatase
source organism Escherichia coli
total genus Genus: 147
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2008-07-07
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3dpcA00
3OT9A 3SZZA 1AJCA 1ALKA 4FDIA 1HJKA 2QZUA 3IGZB 3UN3A 1ELYA 3BDHA 4FDJA 1ZEDA 2ANHA 3T00A 3M8ZA 3MK1A 1KH5A 3MK2A 1KHLA 1N2KA 3MK0A 3BDGB 1URBA 1HQAA 3M8WA 1KH4A 1ALIA 1ZEBA 1AJAA 3T01A 1AJBA 1AJDA 1AUKA 1EJJA 3BDGA 1ELZA 1E33P 1HDHA 3DYCA 3UNYA 1ALJA 1ED8A 1FSUA 3UO0A 3UN2A 1O99A 1E3CP 2GLQA 3M7VA 1KHJA 1KHKA 1Y6VA 3BDFA 1EI6A 1KH9A 1ZEFA 1EW2A 1Y7AA 2IFYA 1N2LA 2G9YA 3SZYA 1SHNA 3NVLA 1E2SP 1EW8A 1ELXA 3IGYB 1ANIA 1O98A 3TX0A 1EQJA 3ED4A 3TWZA 2GA3A 1P49A 1EW9A 1KH7A 1SHQA 1E1ZP 3CMRA 3M8YA 1KHNA 1URAA 1K7HA 1B8JA 3DPCA 3UN5A 3T02A 1ED9A 1ANJA
chains in the KnotProt database with same CATH superfamily
3OT9A 3SZZA 1AJCA 1ALKA 4FDIA 1HJKA 2QZUA 3IGZB 3UN3A 1ELYA 3BDHA 4FDJA 1ZEDA 2ANHA 3T00A 3M8ZA 3MK1A 1KH5A 3MK2A 1KHLA 1N2KA 3MK0A 3BDGB 1URBA 1HQAA 3M8WA 1KH4A 1ALIA 1ZEBA 1AJAA 3T01A 1AJBA 1AJDA 1AUKA 1EJJA 3BDGA 1ELZA 1E33P 1HDHA 3DYCA 3UNYA 1ALJA 1ED8A 1FSUA 3UO0A 3UN2A 1O99A 1E3CP 2GLQA 3M7VA 1KHJA 1KHKA 1Y6VA 3BDFA 1EI6A 1KH9A 1ZEFA 1EW2A 1Y7AA 2IFYA 1N2LA 2G9YA 3SZYA 1SHNA 3NVLA 1E2SP 1EW8A 1ELXA 3IGYB 1ANIA 1O98A 3TX0A 1EQJA 3ED4A 3TWZA 2GA3A 1P49A 1EW9A 1KH7A 1SHQA 1E1ZP 3CMRA 3M8YA 1KHNA 1URAA 1K7HA 1B8JA 3DPCA 3UN5A 3T02A 1ED9A 1ANJA
chains in the KnotProt database with same CATH topology
3OT9A 3SZZA 1AJCA 1ALKA 4FDIA 1HJKA 2QZUA 3IGZB 3UN3A 1ELYA 3BDHA 4FDJA 1ZEDA 2ANHA 3T00A 3M8ZA 3MK1A 1KH5A 3MK2A 1KHLA 1N2KA 3MK0A 3BDGB 1URBA 1HQAA 3M8WA 1KH4A 1ALIA 1ZEBA 1AJAA 3T01A 1AJBA 1AJDA 1AUKA 1EJJA 3BDGA 1ELZA 1E33P 1HDHA 3DYCA 3UNYA 1ALJA 1ED8A 1FSUA 3UO0A 3UN2A 1O99A 1E3CP 2GLQA 3M7VA 1KHJA 1KHKA 1Y6VA 3BDFA 1EI6A 1KH9A 1ZEFA 1EW2A 1Y7AA 2IFYA 1N2LA 2G9YA 3SZYA 1SHNA 3NVLA 1E2SP 1EW8A 1ELXA 3IGYB 1ANIA 1O98A 3TX0A 1EQJA 3ED4A 3TWZA 2GA3A 1P49A 1EW9A 1KH7A 1SHQA 1E1ZP 3CMRA 3M8YA 1KHNA 1URAA 1K7HA 1B8JA 3DPCA 3UN5A 3T02A 1ED9A 1ANJA
chains in the KnotProt database with same CATH homology


 
#chains in the KnotProt database with same CATH superfamily
 3OT9 A;  3SZZ A;  1AJC A;  1ALK A;  4FDI A;  1HJK A;  2QZU A;  3IGZ B;  3UN3 A;  1ELY A;  3BDH A;  4FDJ A;  1ZED A;  2ANH A;  3T00 A;  3M8Z A;  3MK1 A;  1KH5 A;  3MK2 A;  1KHL A;  1N2K A;  3MK0 A;  3BDG B;  1URB A;  1HQA A;  3M8W A;  1KH4 A;  1ALI A;  1ZEB A;  1AJA A;  3T01 A;  1AJB A;  1AJD A;  1AUK A;  1EJJ A;  3BDG A;  1ELZ A;  1E33 P;  1HDH A;  3DYC A;  3UNY A;  1ALJ A;  1ED8 A;  1FSU A;  3UO0 A;  3UN2 A;  1O99 A;  1E3C P;  2GLQ A;  3M7V A;  1KHJ A;  1KHK A;  1Y6V A;  3BDF A;  1EI6 A;  1KH9 A;  1ZEF A;  1EW2 A;  1Y7A A;  2IFY A;  1N2L A;  2G9Y A;  3SZY A;  1SHN A;  3NVL A;  1E2S P;  1EW8 A;  1ELX A;  3IGY B;  1ANI A;  1O98 A;  3TX0 A;  1EQJ A;  3ED4 A;  3TWZ A;  2GA3 A;  1P49 A;  1EW9 A;  1KH7 A;  1SHQ A;  1E1Z P;  3CMR A;  3M8Y A;  1KHN A;  1URA A;  1K7H A;  1B8J A;  3DPC A;  3UN5 A;  3T02 A;  1ED9 A;  1ANJ A; 
#chains in the KnotProt database with same CATH topology
 3OT9 A;  3SZZ A;  1AJC A;  1ALK A;  4FDI A;  1HJK A;  2QZU A;  3IGZ B;  3UN3 A;  1ELY A;  3BDH A;  4FDJ A;  1ZED A;  2ANH A;  3T00 A;  3M8Z A;  3MK1 A;  1KH5 A;  3MK2 A;  1KHL A;  1N2K A;  3MK0 A;  3BDG B;  1URB A;  1HQA A;  3M8W A;  1KH4 A;  1ALI A;  1ZEB A;  1AJA A;  3T01 A;  1AJB A;  1AJD A;  1AUK A;  1EJJ A;  3BDG A;  1ELZ A;  1E33 P;  1HDH A;  3DYC A;  3UNY A;  1ALJ A;  1ED8 A;  1FSU A;  3UO0 A;  3UN2 A;  1O99 A;  1E3C P;  2GLQ A;  3M7V A;  1KHJ A;  1KHK A;  1Y6V A;  3BDF A;  1EI6 A;  1KH9 A;  1ZEF A;  1EW2 A;  1Y7A A;  2IFY A;  1N2L A;  2G9Y A;  3SZY A;  1SHN A;  3NVL A;  1E2S P;  1EW8 A;  1ELX A;  3IGY B;  1ANI A;  1O98 A;  3TX0 A;  1EQJ A;  3ED4 A;  3TWZ A;  2GA3 A;  1P49 A;  1EW9 A;  1KH7 A;  1SHQ A;  1E1Z P;  3CMR A;  3M8Y A;  1KHN A;  1URA A;  1K7H A;  1B8J A;  3DPC A;  3UN5 A;  3T02 A;  1ED9 A;  1ANJ A; 
#chains in the KnotProt database with same CATH homology
 3OT9 A;  3SZZ A;  1AJC A;  1ALK A;  4FDI A;  1HJK A;  2QZU A;  3IGZ B;  3UN3 A;  1ELY A;  3BDH A;  4FDJ A;  1ZED A;  2ANH A;  3T00 A;  3M8Z A;  3MK1 A;  1KH5 A;  3MK2 A;  1KHL A;  1N2K A;  3MK0 A;  3BDG B;  1URB A;  1HQA A;  3M8W A;  1KH4 A;  1ALI A;  1ZEB A;  1AJA A;  3T01 A;  1AJB A;  1AJD A;  1AUK A;  1EJJ A;  3BDG A;  1ELZ A;  1E33 P;  1HDH A;  3DYC A;  3UNY A;  1ALJ A;  1ED8 A;  1FSU A;  3UO0 A;  3UN2 A;  1O99 A;  1E3C P;  2GLQ A;  3M7V A;  1KHJ A;  1KHK A;  1Y6V A;  3BDF A;  1EI6 A;  1KH9 A;  1ZEF A;  1EW2 A;  1Y7A A;  2IFY A;  1N2L A;  2G9Y A;  3SZY A;  1SHN A;  3NVL A;  1E2S P;  1EW8 A;  1ELX A;  3IGY B;  1ANI A;  1O98 A;  3TX0 A;  1EQJ A;  3ED4 A;  3TWZ A;  2GA3 A;  1P49 A;  1EW9 A;  1KH7 A;  1SHQ A;  1E1Z P;  3CMR A;  3M8Y A;  1KHN A;  1URA A;  1K7H A;  1B8J A;  3DPC A;  3UN5 A;  3T02 A;  1ED9 A;  1ANJ A; 
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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